Effects of anesthetics on perioperative short-term outcomes in patients undergoing thoracic surgery with one-lung ventilation

Background: The present study was designed to evaluate the postoperative values such as body temperature (BT), white blood cells (WBC), P/F ratio and C-reactive protein (CRP) associated with propofol or sevoflurane in patients undergoing thoracic surgery with one-lung ventilation. Methods: We retrospectively reviewed outcomes of patients undergoing video-associated thoracic surgery of the esophagus (VATS-E) with propofol (group P, n=71) or sevoflurane (group S, n=34). Data were taken at 1 POD and 2 POD in ICU. In addition, data of WBC and CRP were taken just before the operation and on 5 POD. Statistical analyses used t-value and two-way ANOVA with statistic significance as P<0.05. Results: There was no significant difference between the two groups and we could not find the correlation between anesthetics and each factor. Conclusions: Propofol and sevoflurane had similar effect on BT, WBC, P/F ratio and CRP in patients undergoing thoracic surgery with one-lung ventilation.