Efficient cross-linking to cytidine under neutral conditions using the 2-amino-6-vinylpurine derivative having an additional activating group.

F. Nagatsugi; N. Tokuda; T. Kawasaki; M. Maeda; S. Sasaki

doi:10.1093/nass/1.1.87

Efficient cross-linking to cytidine under neutral conditions using the 2-amino-6-vinylpurine derivative having an additional activating group.

F. Nagatsugi, N. Tokuda, T. Kawasaki, M. Maeda, S. Sasaki

IMRAM - Division of Organic- and Biomaterials Research

Kyushu University

Research output: Contribution to journal › Article › peer-review

Abstract

We have previously reported that the oligonucleotides incorporating 2-amino-6-vinyl purine analog (1) showed efficient interstrand cross-linking with selectivity toward cytidine at a target site. In this paper, we describe the design of more efficient cross-linking reagent (2) bearing 2-amino-6-vinyl purine motif to react to cytidine selectively under neutral condition.

Original language	English
Pages (from-to)	87-88
Number of pages	2
Journal	Nucleic acids research. Supplement (2001)
Issue number	1
DOIs	https://doi.org/10.1093/nass/1.1.87
Publication status	Published - 2001

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10.1093/nass/1.1.87

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title = "Efficient cross-linking to cytidine under neutral conditions using the 2-amino-6-vinylpurine derivative having an additional activating group.",

abstract = "We have previously reported that the oligonucleotides incorporating 2-amino-6-vinyl purine analog (1) showed efficient interstrand cross-linking with selectivity toward cytidine at a target site. In this paper, we describe the design of more efficient cross-linking reagent (2) bearing 2-amino-6-vinyl purine motif to react to cytidine selectively under neutral condition.",

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AU - Maeda, M.

AU - Sasaki, S.

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Efficient cross-linking to cytidine under neutral conditions using the 2-amino-6-vinylpurine derivative having an additional activating group.

Abstract

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