Efficient polymer-assisted strategy for the deprotection of protected oligosaccharides

Hiroshi Tanaka, Tadasuke Ishida, Nobuatsu Matoba, Hirokazu Tsukamoto, Haruo Yamada, Takashi Takahashi

Research output: Contribution to journalArticlepeer-review

13 Citations (Scopus)


(Chemical Equation Presented) New strategies in sugar synthesis: A prelinker containing a dihydropyranyl moiety and an activated ester can be attached to a sugar, which is then loaded onto an amino-modified support by amidation. Standard protecting-group manipulations are possible. Final cleavage of the linker under mildly acidic conditions provides the fully deprotected oligosaccharides. TFA=trifluoroacetic acid.

Original languageEnglish
Pages (from-to)6349-6352
Number of pages4
JournalAngewandte Chemie - International Edition
Issue number38
Publication statusPublished - 2006 Sept 25


  • Birch reduction
  • Glycoconjugates
  • Glycosylation
  • Oligosaccharides
  • Solid-phase synthesis

ASJC Scopus subject areas

  • Catalysis
  • Chemistry(all)


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