Abstract
The recent progress of highly selective titanium reagents in organic synthesis is reviewed. The use of titanium reagents is classified into the following six categories: (1) Bi-metallic reagents of titanium and main group elements, aluminum in particular, for olefination. (2) Alkyltitanium reagents for carbon-carbon bond formation. (3) Titanium enolates for aldol condensation. (4) Chiral titanium complexes for asymmetric Lewis-acid catalysis. (5) Low valent titanium reagents for reductive coupling reaction. (6) Sharpless reagent for asymmetric epoxidation.
| Original language | English |
|---|---|
| Pages (from-to) | 566-574 |
| Number of pages | 9 |
| Journal | Yuki Gosei Kagaku Kyokaishi/Journal of Synthetic Organic Chemistry |
| Volume | 49 |
| Issue number | 6 |
| DOIs | |
| Publication status | Published - 1991 |
Keywords
- Alkyltitanium reagents
- Asymmetric catalysis
- Chemoselectivity
- Chiral titanium complexes
- Coupling reaction
- Diastereoselectivity
- Diels-Alder reaction
- Enantios-electivity
- Ene reaction
- Hetero bi-metallic reagents
- Hydroalumination
- Hydromagnesiation
- Hydrotitanation
- Kinetic resolution
- Lewis acid
- Low valent titanium reagents
- Olefin methathesis
- Olefination
- Regioselectivity
- Sharpless epoxidation
- Stereoselectivity
- Tebbe reagent
- Titanium enolates