TY - JOUR
T1 - Electrochemical determination of choline using nortropine-N-oxyl for a non-enzymatic system
AU - Kashiwagi, Yoshitomo
AU - Ono, Tetsuya
AU - Sato, Fumiya
AU - Kumano, Masayuki
AU - Yoshida, Kentaro
AU - Dairaku, Takenori
AU - Sasano, Yusuke
AU - Iwabuchi, Yoshiharu
AU - Sato, Katsuhiko
N1 - Funding Information:
This work was supported by JSPS KAKENHI Grant Number JP16K08189 , JP18K06791 and JP18K19936 . The Foundation for Ohu University Joint Research Fund and the Research Funding Granted by Ohu University President is also acknowledged for financial support. Appendix A
Funding Information:
This work was supported by JSPS KAKENHI Grant Number JP16K08189, JP18K06791 and JP18K19936. The Foundation for Ohu University Joint Research Fund and the Research Funding Granted by Ohu University President is also acknowledged for financial support.
Publisher Copyright:
© 2019
PY - 2020/2
Y1 - 2020/2
N2 - The electrocatalytical activity of nortropine-N-oxyl (NNO) was evaluated by cyclic voltammetry in pH 7.4 phosphate buffer solution. The anodic peak current for choline was enhanced in a concentration-dependent fashion, showing that choline was oxidized by the electrocatalytic effect of NNO. A high linear response to the choline concentration ranging from 0.1 to 10 mM was obtained. In contrast, 2,2,6,6-tetramethylpiperidine-N-oxyl (TEMPO) could not oxidize choline under the same conditions.
AB - The electrocatalytical activity of nortropine-N-oxyl (NNO) was evaluated by cyclic voltammetry in pH 7.4 phosphate buffer solution. The anodic peak current for choline was enhanced in a concentration-dependent fashion, showing that choline was oxidized by the electrocatalytic effect of NNO. A high linear response to the choline concentration ranging from 0.1 to 10 mM was obtained. In contrast, 2,2,6,6-tetramethylpiperidine-N-oxyl (TEMPO) could not oxidize choline under the same conditions.
KW - Choline
KW - Electrocatalytic oxidation
KW - Nitroxyl radical
KW - Non-enzymatic system
UR - http://www.scopus.com/inward/record.url?scp=85077901487&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=85077901487&partnerID=8YFLogxK
U2 - 10.1016/j.sbsr.2019.100302
DO - 10.1016/j.sbsr.2019.100302
M3 - Article
AN - SCOPUS:85077901487
SN - 2214-1804
VL - 27
JO - Sensing and Bio-Sensing Research
JF - Sensing and Bio-Sensing Research
M1 - 100302
ER -