Abstract
trans- and cis-3-Aminoindan-1-ols were prepared by moderately selective reductions of 3-aminoindan-1-one derivatives and separated into enantiopure forms. The enantiopure trans-isomer had a moderate resolving ability for 2-arylalkanoic acids having a naphthalene ring at the α-position. The X-ray crystallographic analysis showed that an infinite hydrogen-bond sheet was formed in the less-soluble salt, suggesting that the skeleton of these indanols would be favorable for the stabilization of the less-soluble salt by hydrogen-bonding interaction.
| Original language | English |
|---|---|
| Pages (from-to) | 266-267 |
| Number of pages | 2 |
| Journal | Chemistry Letters |
| Issue number | 3 |
| DOIs | |
| Publication status | Published - 2002 Mar 5 |
| Externally published | Yes |
ASJC Scopus subject areas
- Chemistry(all)