Enzyme Sensors Based on a Coated-Wire Electrode: Effects of Buffer Concentration and pH on the Potentiometric Response of Penicillin Sensor

Chien wu Chen; Jun ichi Anzai; Tetsuo Osa

doi:10.1248/cpb.36.3671

Enzyme Sensors Based on a Coated-Wire Electrode: Effects of Buffer Concentration and pH on the Potentiometric Response of Penicillin Sensor

Chien wu Chen, Jun ichi Anzai, Tetsuo Osa

PHA - Molecular Pharmaceutical Science

Research output: Contribution to journal › Article › peer-review

8 Citations (Scopus)

Abstract

The effects of pH and concentration of working buffer on the potentiometric response of a penicillin sensor based on a carboxyl-substituted poly (vinyl chloride)-coated Ag electrode were examined. The sensor showed a good response in buffer solutions of pH 6.5—8.5. The buffer concentration affected the response of the sensor. Higher concentration buffer (30 mM) strongly disturbed the response due to the higher buffer capacity.

Original language	English
Pages (from-to)	3671-3674
Number of pages	4
Journal	Chemical and Pharmaceutical Bulletin
Volume	36
Issue number	9
DOIs	https://doi.org/10.1248/cpb.36.3671
Publication status	Published - 1988

Keywords

carboxvl
coated-wire electrode
enzvme sensor
penicillin sensor
penicillinase
substituted poly(vinyl chloride)

ASJC Scopus subject areas

Chemistry(all)
Drug Discovery

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AU - Osa, Tetsuo

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AB - The effects of pH and concentration of working buffer on the potentiometric response of a penicillin sensor based on a carboxyl-substituted poly (vinyl chloride)-coated Ag electrode were examined. The sensor showed a good response in buffer solutions of pH 6.5—8.5. The buffer concentration affected the response of the sensor. Higher concentration buffer (30 mM) strongly disturbed the response due to the higher buffer capacity.

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Enzyme Sensors Based on a Coated-Wire Electrode: Effects of Buffer Concentration and pH on the Potentiometric Response of Penicillin Sensor

Abstract

Keywords

ASJC Scopus subject areas

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