TY - GEN
T1 - Evaluation of a cleaning process inside a microfluidic channel using a single-chip QCM array
AU - Abe, Takashi
AU - Itasaka, Yousuke
AU - Kaji, Hirokazu
AU - Nishizawa, Matsuhiko
PY - 2009
Y1 - 2009
N2 - This paper reports a cleaning method for sensor array inside a packaged micro-fluidic device and the evaluation method. A single-chip quartz-crystal microbalance (QCM) array was used as a model of sensor array since it can evaluate the cleaning process in real-time. By locally generating HBrO and Br - at a working electrode in the microfluidic device, gold electrode of the QCM was etched at an atomic layer level. Since the HBrO removes blocking agent on the electrode of QCM, it allows also site-specific immobilization of materials by introducing materials of interest into the device. This method is expected to use as a simple method for cleaning and surface modification of sensor array after assembling the microfluidic device.
AB - This paper reports a cleaning method for sensor array inside a packaged micro-fluidic device and the evaluation method. A single-chip quartz-crystal microbalance (QCM) array was used as a model of sensor array since it can evaluate the cleaning process in real-time. By locally generating HBrO and Br - at a working electrode in the microfluidic device, gold electrode of the QCM was etched at an atomic layer level. Since the HBrO removes blocking agent on the electrode of QCM, it allows also site-specific immobilization of materials by introducing materials of interest into the device. This method is expected to use as a simple method for cleaning and surface modification of sensor array after assembling the microfluidic device.
KW - Array
KW - Cleaning
KW - Microfluidic
KW - QCM
KW - Surface modification
UR - http://www.scopus.com/inward/record.url?scp=84901814936&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=84901814936&partnerID=8YFLogxK
M3 - Conference contribution
AN - SCOPUS:84901814936
SN - 9780979806421
T3 - Proceedings of Conference, MicroTAS 2009 - The 13th International Conference on Miniaturized Systems for Chemistry and Life Sciences
SP - 1650
EP - 1652
BT - Proceedings of Conference, MicroTAS 2009 - The 13th International Conference on Miniaturized Systems for Chemistry and Life Sciences
PB - Chemical and Biological Microsystems Society
T2 - 13th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2009
Y2 - 1 November 2009 through 5 November 2009
ER -