Evaluation of cerebral blood flow and metabolism in childhood moyamoya disease: an investigation into "re-build-up" on EEG by positron CT

Motonobu Kameyama; Reizo Shirane; Yuji Tsurumi; Akira Takahashi; Satoru Fujiwara; Jiro Suzuki; Masatoshi Ito; Tatsuo Ido

doi:10.1007/BF00270840

Evaluation of cerebral blood flow and metabolism in childhood moyamoya disease: an investigation into "re-build-up" on EEG by positron CT

Motonobu Kameyama, Reizo Shirane, Yuji Tsurumi, Akira Takahashi, Satoru Fujiwara, Jiro Suzuki, Masatoshi Ito, Tatsuo Ido

Cyclotron and Radioisotope Center (CYRIC)

Research output: Contribution to journal › Article › peer-review

26 Citations (Scopus)

Abstract

The cerebral blood flow and cerebral metabolic rate of oxygen (CBF and CMRO₂) of three cases of childhood moyamoya disease were examined by positron-emission-computed tomography for the purpose of investigating the mechanism of the "re-build-up" phenomenon on EEG. Decrease in both CBF and CMRO₂ were observed following hyperventilation. However, dissociation between the decrease in CBF and CMRO₂ was also observed. Arterial blood-gas analysis disclosed hypocapnea during hyperventilation and hypoxia following hyperventilation. These results clearly indicate that the re-build-up seen on EEG is the manifestation not only of ischemic hypoxia but also of hypoxic hypoxia characteristically seen in moyamoya disease.

Original language	English
Pages (from-to)	130-133
Number of pages	4
Journal	Child's Nervous System
Volume	2
Issue number	3
DOIs	https://doi.org/10.1007/BF00270840
Publication status	Published - 1986 Sept

Keywords

Cerebral blood flow
Cerebral metabolism
EEG
Moyamoya disease
Positron CT
Re-build-up

ASJC Scopus subject areas

Pediatrics, Perinatology, and Child Health
Clinical Neurology

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10.1007/BF00270840

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title = "Evaluation of cerebral blood flow and metabolism in childhood moyamoya disease: an investigation into {"}re-build-up{"} on EEG by positron CT",

abstract = "The cerebral blood flow and cerebral metabolic rate of oxygen (CBF and CMRO2) of three cases of childhood moyamoya disease were examined by positron-emission-computed tomography for the purpose of investigating the mechanism of the {"}re-build-up{"} phenomenon on EEG. Decrease in both CBF and CMRO2 were observed following hyperventilation. However, dissociation between the decrease in CBF and CMRO2 was also observed. Arterial blood-gas analysis disclosed hypocapnea during hyperventilation and hypoxia following hyperventilation. These results clearly indicate that the re-build-up seen on EEG is the manifestation not only of ischemic hypoxia but also of hypoxic hypoxia characteristically seen in moyamoya disease.",

keywords = "Cerebral blood flow, Cerebral metabolism, EEG, Moyamoya disease, Positron CT, Re-build-up",

author = "Motonobu Kameyama and Reizo Shirane and Yuji Tsurumi and Akira Takahashi and Satoru Fujiwara and Jiro Suzuki and Masatoshi Ito and Tatsuo Ido",

year = "1986",

month = sep,

doi = "10.1007/BF00270840",

language = "English",

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T1 - Evaluation of cerebral blood flow and metabolism in childhood moyamoya disease

T2 - an investigation into "re-build-up" on EEG by positron CT

AU - Kameyama, Motonobu

AU - Shirane, Reizo

AU - Tsurumi, Yuji

AU - Takahashi, Akira

AU - Fujiwara, Satoru

AU - Suzuki, Jiro

AU - Ito, Masatoshi

AU - Ido, Tatsuo

PY - 1986/9

Y1 - 1986/9

N2 - The cerebral blood flow and cerebral metabolic rate of oxygen (CBF and CMRO2) of three cases of childhood moyamoya disease were examined by positron-emission-computed tomography for the purpose of investigating the mechanism of the "re-build-up" phenomenon on EEG. Decrease in both CBF and CMRO2 were observed following hyperventilation. However, dissociation between the decrease in CBF and CMRO2 was also observed. Arterial blood-gas analysis disclosed hypocapnea during hyperventilation and hypoxia following hyperventilation. These results clearly indicate that the re-build-up seen on EEG is the manifestation not only of ischemic hypoxia but also of hypoxic hypoxia characteristically seen in moyamoya disease.

AB - The cerebral blood flow and cerebral metabolic rate of oxygen (CBF and CMRO2) of three cases of childhood moyamoya disease were examined by positron-emission-computed tomography for the purpose of investigating the mechanism of the "re-build-up" phenomenon on EEG. Decrease in both CBF and CMRO2 were observed following hyperventilation. However, dissociation between the decrease in CBF and CMRO2 was also observed. Arterial blood-gas analysis disclosed hypocapnea during hyperventilation and hypoxia following hyperventilation. These results clearly indicate that the re-build-up seen on EEG is the manifestation not only of ischemic hypoxia but also of hypoxic hypoxia characteristically seen in moyamoya disease.

KW - Cerebral blood flow

KW - Cerebral metabolism

KW - EEG

KW - Moyamoya disease

KW - Positron CT

KW - Re-build-up

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Evaluation of cerebral blood flow and metabolism in childhood moyamoya disease: an investigation into "re-build-up" on EEG by positron CT

Abstract

Keywords

ASJC Scopus subject areas

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