Evaluation of total peripheral resistance in using a left ventricular assist device

H. Akiho; S. Nitta; T. Yambe; S. Naganuma; Y. Kakinuma; K. Izutsu; S. Kobayashi; S. Nanka; M. Tanaka; T. Fukuju; M. Miura; N. Sato; H. Mohri; S. Koide; K. Abe; H. Takeda; T. Kasai; H. Hashimoto; M. Yoshizawa

Evaluation of total peripheral resistance in using a left ventricular assist device

H. Akiho, S. Nitta, T. Yambe, S. Naganuma, Y. Kakinuma, K. Izutsu, S. Kobayashi, S. Nanka, M. Tanaka, T. Fukuju, M. Miura, N. Sato, H. Mohri, S. Koide, K. Abe, H. Takeda, T. Kasai, H. Hashimoto, M. Yoshizawa

IDAC - PreClinical Research Center

Tohoku University

Research output: Contribution to journal › Article › peer-review

Abstract

To determine optimal driving modes of left ventricular assist device (LVAD) for the natural heart, acute experiments were performed in 8 adult goats. LVAD bypass flow was maintained within same value during the use of co-pulsation mode and conterpulsation mode by our adaptive control system. Total peripheral vascular resistance and natural heart output during each driving mode were evaluated. Total peripheral resistances were not significantly changed during each driving mode though natural heart output increased during the use of counterpulsation mode compared with co-pulsation mode. These results suggested that afterload of the natural heart was decreased during the use of counterpulsation mode and counterpulsation mode was desirable for the natural heart unloading.

Original language	English
Pages (from-to)	71-75
Number of pages	5
Journal	Japanese Journal of Artificial Organs
Volume	23
Issue number	1
Publication status	Published - 1994

Cite this

Akiho, H., Nitta, S., Yambe, T., Naganuma, S., Kakinuma, Y., Izutsu, K., Kobayashi, S., Nanka, S., Tanaka, M., Fukuju, T., Miura, M., Sato, N., Mohri, H., Koide, S., Abe, K., Takeda, H., Kasai, T., Hashimoto, H., & Yoshizawa, M. (1994). Evaluation of total peripheral resistance in using a left ventricular assist device. Japanese Journal of Artificial Organs, 23(1), 71-75.

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title = "Evaluation of total peripheral resistance in using a left ventricular assist device",

abstract = "To determine optimal driving modes of left ventricular assist device (LVAD) for the natural heart, acute experiments were performed in 8 adult goats. LVAD bypass flow was maintained within same value during the use of co-pulsation mode and conterpulsation mode by our adaptive control system. Total peripheral vascular resistance and natural heart output during each driving mode were evaluated. Total peripheral resistances were not significantly changed during each driving mode though natural heart output increased during the use of counterpulsation mode compared with co-pulsation mode. These results suggested that afterload of the natural heart was decreased during the use of counterpulsation mode and counterpulsation mode was desirable for the natural heart unloading.",

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AU - Akiho, H.

AU - Nitta, S.

AU - Yambe, T.

AU - Naganuma, S.

AU - Kakinuma, Y.

AU - Izutsu, K.

AU - Kobayashi, S.

AU - Nanka, S.

AU - Tanaka, M.

AU - Fukuju, T.

AU - Miura, M.

AU - Sato, N.

AU - Mohri, H.

AU - Koide, S.

AU - Abe, K.

AU - Takeda, H.

AU - Kasai, T.

AU - Hashimoto, H.

AU - Yoshizawa, M.

PY - 1994

Y1 - 1994

N2 - To determine optimal driving modes of left ventricular assist device (LVAD) for the natural heart, acute experiments were performed in 8 adult goats. LVAD bypass flow was maintained within same value during the use of co-pulsation mode and conterpulsation mode by our adaptive control system. Total peripheral vascular resistance and natural heart output during each driving mode were evaluated. Total peripheral resistances were not significantly changed during each driving mode though natural heart output increased during the use of counterpulsation mode compared with co-pulsation mode. These results suggested that afterload of the natural heart was decreased during the use of counterpulsation mode and counterpulsation mode was desirable for the natural heart unloading.

AB - To determine optimal driving modes of left ventricular assist device (LVAD) for the natural heart, acute experiments were performed in 8 adult goats. LVAD bypass flow was maintained within same value during the use of co-pulsation mode and conterpulsation mode by our adaptive control system. Total peripheral vascular resistance and natural heart output during each driving mode were evaluated. Total peripheral resistances were not significantly changed during each driving mode though natural heart output increased during the use of counterpulsation mode compared with co-pulsation mode. These results suggested that afterload of the natural heart was decreased during the use of counterpulsation mode and counterpulsation mode was desirable for the natural heart unloading.

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Evaluation of total peripheral resistance in using a left ventricular assist device

Abstract

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