Experimentally Induced Mammalian Models of Glaucoma

Makoto Ishikawa, Takeshi Yoshitomi, Charles F. Zorumski, Yukitoshi Izumi

Research output: Contribution to journalReview articlepeer-review

47 Citations (Scopus)


A wide variety of animal models have been used to study glaucoma. Although these models provide valuable information about the disease, there is still no ideal model for studying glaucoma due to its complex pathogenesis. Animal models for glaucoma are pivotal for clarifying glaucoma etiology and for developing novel therapeutic strategies to halt disease progression. In this review paper, we summarize some of the major findings obtained in various glaucoma models and examine the strengths and limitations of these models.

Original languageEnglish
Article number281214
JournalBioMed Research International
Publication statusPublished - 2015


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