TY - JOUR
T1 - Exploiting ruthenium carbene-catalyzed reactions in total synthesis of marine oxacyclic natural products
AU - Fuwa, Haruhiko
AU - Sasaki, Makoto
N1 - Publisher Copyright:
© 2016 The Chemical Society of Japan.
PY - 2016
Y1 - 2016
N2 - Olefin metathesis has emerged as an indispensable means to create complex natural products by the virtue of its powerful carboncarbon bond-forming ability, compatibility with a range of functional groups, and ready availability of highly reactive ruthenium carbene catalysts. Furthermore, Grubbs-type ruthenium carbene complexes originally developed for olefin metathesis reactions also mediate a variety of non-metathetic reactions and found their use in tandem metathetic/nonmetathetic processes. This account summarizes our recent efforts on total synthesis of oxacyclic natural products by means of ruthenium carbene-catalyzed reactions.
AB - Olefin metathesis has emerged as an indispensable means to create complex natural products by the virtue of its powerful carboncarbon bond-forming ability, compatibility with a range of functional groups, and ready availability of highly reactive ruthenium carbene catalysts. Furthermore, Grubbs-type ruthenium carbene complexes originally developed for olefin metathesis reactions also mediate a variety of non-metathetic reactions and found their use in tandem metathetic/nonmetathetic processes. This account summarizes our recent efforts on total synthesis of oxacyclic natural products by means of ruthenium carbene-catalyzed reactions.
UR - http://www.scopus.com/inward/record.url?scp=85025835635&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=85025835635&partnerID=8YFLogxK
U2 - 10.1246/bcsj.20160224
DO - 10.1246/bcsj.20160224
M3 - Article
AN - SCOPUS:85025835635
SN - 0009-2673
VL - 89
SP - 1403
EP - 1415
JO - Bulletin of the Chemical Society of Japan
JF - Bulletin of the Chemical Society of Japan
IS - 12
ER -
