Fabrication of tissue compatible phospholipid polymer matrix for 3D cell culture

Eri Maeta, Tomohiro Konno, Madoka Takai, Kazuhiko Ishihara

Research output: Contribution to conferencePaperpeer-review


Recently, tissue engineering scaffolds are investigated from various biological materials. In this study, we use a phospholipid polymer (PMBN) composed of 2-methacryloyloxyethyl phosphorylcholine (MPC), n-butyl methacrylate (BMA), and p-nitrophenyloxycarbonyl poly(oxyethylene)methacrylate (MEO 2NP). PMBN hydrogel was fabricated by reaction with Bis (3-aminopropyl) poly (ethylene oxide) , in order to achieve a novel polymer matrix for cell culture that enables to control cell adhesions. The PMBN hydrogel has uniform several micrometers porous texture, therefore , PMBN hydrogel conjugated the adhesion molecule, Arg-Gly-Asp-Ser(RGDS), would become novel scaffold for 3D cell culture.

Original languageEnglish
Number of pages2
Publication statusPublished - 2005 Dec 1
Externally publishedYes
Event54th SPSJ Symposium on Macromolecules - Yamagata, Japan
Duration: 2005 Sept 202005 Sept 22


Other54th SPSJ Symposium on Macromolecules


  • 3D Scaffold
  • Bio-conjugate
  • Hydrogel
  • Phospholipid polymer

ASJC Scopus subject areas

  • Engineering(all)


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