Facile synthesis of 3,4-dihalofurans via electrophilic iodocyclization

Fan Yang; Tienan Jin; Ming Bao; Yoshinori Yamamoto

doi:10.1039/c1cc10584a

Facile synthesis of 3,4-dihalofurans via electrophilic iodocyclization

Fan Yang, Tienan Jin, Ming Bao, Yoshinori Yamamoto

SCI - Research and Analytical Center for Giant Molecules

Research output: Contribution to journal › Article › peer-review

48 Citations (Scopus)

Abstract

A facile, efficient, and general synthetic method for 3,4-dihalofurans has been developed via the electrophilic iodocyclization of various 4-hydroxy-2-but-2-yn-1-ones. The use of MeOH as a solvent is crucial for the efficient chemoselective synthesis of the corresponding 3,4-dihalofurans.

Original language	English
Pages (from-to)	4541-4543
Number of pages	3
Journal	Chemical Communications
Volume	47
Issue number	15
DOIs	https://doi.org/10.1039/c1cc10584a
Publication status	Published - 2011 Mar 29

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abstract = "A facile, efficient, and general synthetic method for 3,4-dihalofurans has been developed via the electrophilic iodocyclization of various 4-hydroxy-2-but-2-yn-1-ones. The use of MeOH as a solvent is crucial for the efficient chemoselective synthesis of the corresponding 3,4-dihalofurans.",

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AU - Yamamoto, Yoshinori

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AB - A facile, efficient, and general synthetic method for 3,4-dihalofurans has been developed via the electrophilic iodocyclization of various 4-hydroxy-2-but-2-yn-1-ones. The use of MeOH as a solvent is crucial for the efficient chemoselective synthesis of the corresponding 3,4-dihalofurans.

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Facile synthesis of 3,4-dihalofurans via electrophilic iodocyclization

Abstract

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