FDG PET for esophageal cancer complicated by sarcoidosis mimicking mediastinal and hilar lymph node metastases: Two case reports

Kentaro Takanami; Tomohiro Kaneta; Takayuki Yamada; Shigeo Kinomura; Shogo Yamada; Hiroshi Fukuda; Shoki Takahashi

doi:10.1097/RLU.0b013e3181662fda

FDG PET for esophageal cancer complicated by sarcoidosis mimicking mediastinal and hilar lymph node metastases: Two case reports

Kentaro Takanami, Tomohiro Kaneta, Takayuki Yamada, Shigeo Kinomura, Shogo Yamada, Hiroshi Fukuda, Shoki Takahashi

Tohoku University

Research output: Contribution to journal › Article › peer-review

14 Citations (Scopus)

Abstract

This report documents 2 cases of esophageal cancer complicated by sarcoidosis mimicking mediastinal lymph node metastases on F-18 fluorodeoxyglucose positron emission tomography (FDG PET) for staging of the cancer. In both cases, FDG PET demonstrated intense uptake in the swollen mediastinal and bilateral hilar lymph nodes. In 1 case, FDG PET showed intense uptake in the primary esophageal cancer. In another case, FDG PET showed no definite intense uptake in the primary esophageal cancer. The histopathology of the resected mediastinal and hilar lymph nodes demonstrated no malignant cells but sarcoid lesions such as noncaseating granuloma. Therefore, sarcoidosis should be considered when FDG PET shows intense FDG uptake in nonregional swollen lymph nodes, although the incidence of esophageal cancer complicated by sarcoidosis is rare.

Original language	English
Pages (from-to)	258-261
Number of pages	4
Journal	Clinical Nuclear Medicine
Volume	33
Issue number	4
DOIs	https://doi.org/10.1097/RLU.0b013e3181662fda
Publication status	Published - 2008 Apr

Keywords

Esophageal cancer
FDG
Sarcoidosis

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

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10.1097/RLU.0b013e3181662fda

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title = "FDG PET for esophageal cancer complicated by sarcoidosis mimicking mediastinal and hilar lymph node metastases: Two case reports",

abstract = "This report documents 2 cases of esophageal cancer complicated by sarcoidosis mimicking mediastinal lymph node metastases on F-18 fluorodeoxyglucose positron emission tomography (FDG PET) for staging of the cancer. In both cases, FDG PET demonstrated intense uptake in the swollen mediastinal and bilateral hilar lymph nodes. In 1 case, FDG PET showed intense uptake in the primary esophageal cancer. In another case, FDG PET showed no definite intense uptake in the primary esophageal cancer. The histopathology of the resected mediastinal and hilar lymph nodes demonstrated no malignant cells but sarcoid lesions such as noncaseating granuloma. Therefore, sarcoidosis should be considered when FDG PET shows intense FDG uptake in nonregional swollen lymph nodes, although the incidence of esophageal cancer complicated by sarcoidosis is rare.",

keywords = "Esophageal cancer, FDG, Sarcoidosis",

author = "Kentaro Takanami and Tomohiro Kaneta and Takayuki Yamada and Shigeo Kinomura and Shogo Yamada and Hiroshi Fukuda and Shoki Takahashi",

year = "2008",

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T1 - FDG PET for esophageal cancer complicated by sarcoidosis mimicking mediastinal and hilar lymph node metastases

T2 - Two case reports

AU - Takanami, Kentaro

AU - Kaneta, Tomohiro

AU - Yamada, Takayuki

AU - Kinomura, Shigeo

AU - Yamada, Shogo

AU - Fukuda, Hiroshi

AU - Takahashi, Shoki

PY - 2008/4

Y1 - 2008/4

N2 - This report documents 2 cases of esophageal cancer complicated by sarcoidosis mimicking mediastinal lymph node metastases on F-18 fluorodeoxyglucose positron emission tomography (FDG PET) for staging of the cancer. In both cases, FDG PET demonstrated intense uptake in the swollen mediastinal and bilateral hilar lymph nodes. In 1 case, FDG PET showed intense uptake in the primary esophageal cancer. In another case, FDG PET showed no definite intense uptake in the primary esophageal cancer. The histopathology of the resected mediastinal and hilar lymph nodes demonstrated no malignant cells but sarcoid lesions such as noncaseating granuloma. Therefore, sarcoidosis should be considered when FDG PET shows intense FDG uptake in nonregional swollen lymph nodes, although the incidence of esophageal cancer complicated by sarcoidosis is rare.

AB - This report documents 2 cases of esophageal cancer complicated by sarcoidosis mimicking mediastinal lymph node metastases on F-18 fluorodeoxyglucose positron emission tomography (FDG PET) for staging of the cancer. In both cases, FDG PET demonstrated intense uptake in the swollen mediastinal and bilateral hilar lymph nodes. In 1 case, FDG PET showed intense uptake in the primary esophageal cancer. In another case, FDG PET showed no definite intense uptake in the primary esophageal cancer. The histopathology of the resected mediastinal and hilar lymph nodes demonstrated no malignant cells but sarcoid lesions such as noncaseating granuloma. Therefore, sarcoidosis should be considered when FDG PET shows intense FDG uptake in nonregional swollen lymph nodes, although the incidence of esophageal cancer complicated by sarcoidosis is rare.

KW - Esophageal cancer

KW - FDG

KW - Sarcoidosis

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ER -

FDG PET for esophageal cancer complicated by sarcoidosis mimicking mediastinal and hilar lymph node metastases: Two case reports

Abstract

Keywords

UN SDGs

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