Fluid status and its management in Japanese peritoneal dialysis patients

Masaaki Nakayama

Research output: Contribution to journalReview articlepeer-review

10 Citations (Scopus)


This article reviews published studies related to fluid status of Japanese peritoneal dialysis (PD) patients and its impact on technique and patient survival. In addition, some specifics related to clinical background that potentially influence fluid status are described. According to a multicenter survey conducted in Japan, nearly 25% of Japanese PD patients are overhydrated. Available data indicate that a high salt diet may conceivably play an important role in the pathogenesis of fluid overload in Japanese PD patients, and it in turn negatively impacts patient prognosis. Because of the generally adopted policy among Japanese PD experts to avoid regular use of 3.86% glucose solution, icodextrin solution is now used in more than one third of all patients. Other means of managing fluid overload, such as drug therapy, combination (complementary) therapy with hemodialysis, and low sodium PD solution, are also explored and summarized in this article.

Original languageEnglish
Pages (from-to)144-149
Number of pages6
JournalPeritoneal Dialysis International
Issue number2
Publication statusPublished - 2006
Externally publishedYes


  • Blood pressure
  • Combination therapy
  • Fluid status
  • Hypervolemia
  • Japan
  • Low sodium solution
  • Overhydration
  • Salt intake
  • Tranexamic acid

ASJC Scopus subject areas

  • Nephrology


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