TY - JOUR
T1 - Fluorescein Angiography Scoring System Using Ultra-Wide–Field Fluorescein Angiography Versus Standard Fluorescein Angiography in Patients with Sarcoid Uveitis
AU - Tanaka, Rie
AU - Kaburaki, Toshikatsu
AU - Yoshida, Atsushi
AU - Takamoto, Mitsuko
AU - Miyaji, Tempei
AU - Yamaguchi, Takuhiro
N1 - Funding Information:
This work was supported by JSPS KAKENHI [grant numbers 16K11281 and 19K09986]. We thank Fukumi Fujikake for taking the fluorescein angiography photographs. The manuscript was edited for English grammar by a native writer at Enago.
Publisher Copyright:
© 2020 Taylor & Francis Group, LLC.
PY - 2021
Y1 - 2021
N2 - Purpose: To compare standard fluorescein angiography (FA) and ultra-wide-field (UWF) FA in evaluating sarcoid uveitis activity using the scoring system adopted by the Angiography Scoring for Uveitis Working Group (ASUWG). Methods: Standard and UWF FA images of 36 eyes with sarcoid uveitis were acquired on the same day. Three graders independently graded 72 FA images using the ASUWG scoring system. We evaluated inter-observer variability using the intra-class correlation coefficient (ICC) and compared scores of each angiographic sign. Results: The ICC was 0.77 for standard FA and 0.87 for UWF FA, with respective total scores of 12.0 and 14.6. UWF FA had higher scores than standard FA for optic disc hyperfluorescence, posterior retinal vascular staining and/or leakage, and peripheral capillary leakage. Conclusions: The scores for UWF FA had a higher ICC than those for standard FA in evaluating sarcoid uveitis. Peripheral capillary leakage scores were particularly high for UWF FA.
AB - Purpose: To compare standard fluorescein angiography (FA) and ultra-wide-field (UWF) FA in evaluating sarcoid uveitis activity using the scoring system adopted by the Angiography Scoring for Uveitis Working Group (ASUWG). Methods: Standard and UWF FA images of 36 eyes with sarcoid uveitis were acquired on the same day. Three graders independently graded 72 FA images using the ASUWG scoring system. We evaluated inter-observer variability using the intra-class correlation coefficient (ICC) and compared scores of each angiographic sign. Results: The ICC was 0.77 for standard FA and 0.87 for UWF FA, with respective total scores of 12.0 and 14.6. UWF FA had higher scores than standard FA for optic disc hyperfluorescence, posterior retinal vascular staining and/or leakage, and peripheral capillary leakage. Conclusions: The scores for UWF FA had a higher ICC than those for standard FA in evaluating sarcoid uveitis. Peripheral capillary leakage scores were particularly high for UWF FA.
KW - Ocular sarcoidosis
KW - fluorescein angiography scoring system
KW - sarcoid uveitis
KW - ultra-wide–field fluorescein angiography
KW - ultra-wide–field scanning laser ophthalmoscopy
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U2 - 10.1080/09273948.2020.1737141
DO - 10.1080/09273948.2020.1737141
M3 - Article
C2 - 32162984
AN - SCOPUS:85081737781
SN - 0927-3948
VL - 29
SP - 1398
EP - 1402
JO - Ocular Immunology and Inflammation
JF - Ocular Immunology and Inflammation
IS - 7-8
ER -