Abstract
The formation of genotoxic bifunctional electrophiles from arachidonic acid hydroperoxides during vitamin C-mediated decomposition was investigated. The normal phase LC/tandem mass spectrometry analysis (MS/MS) were used for the study. It was found that the reaction with vitamin C and 15-HpETE produced a product profile that was distinct in its major products produced. It was also found that vitamin E was just as potent as vitamin C in mediating the formation of bifunctional electrophiles.
| Original language | English |
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| Pages | 607-608 |
| Number of pages | 2 |
| Publication status | Published - 2002 |
| Event | Proceedings - 50th ASMS Conference on Mass Spectrometry and Allied Topics - Orlando, FL, United States Duration: 2002 Jun 2 → 2002 Jun 6 |
Conference
| Conference | Proceedings - 50th ASMS Conference on Mass Spectrometry and Allied Topics |
|---|---|
| Country/Territory | United States |
| City | Orlando, FL |
| Period | 02/6/2 → 02/6/6 |