Functional disorders of the temporomandibular joints: Internal derangement of the temporomandibular joint

Chih Ling Chang, Ding Han Wang, Mu Chen Yang, Wun Eng Hsu, Ming Lun Hsu

Research output: Contribution to journalReview articlepeer-review

29 Citations (Scopus)


Temporomandibular joint (TMJ) is one of the most complex joints of the human body. Due to its unique movement, in terms of combination of rotation and translator movement, disc of the joint plays an important role to maintain its normal function. In order to sustain the normal function of the TMJ, disc must be kept in proper position as well as maintain normal shape in all circumstances. Once the disc is not any more in its normal position during function of the joint, disturbance of the joint can be occurred which will lead to subsequent distortion of the disc. Shape of the disc can be influenced by many factors i.e.: abnormal function or composition of the disc itself. Etiology of the internal derangement of the disc remains controversial. Multifactorial theory has been postulated in most of previous manuscripts. Disc is composed of mainly extracellular matrix. Abnormal proportion of collagen type I & III may also leads to joint hypermobility which may be also a predisposing factor of this disorder. Thus it can be recognized as local manifestation of a systemic disorder. Different treatment modalities with from conservative treatment to surgical intervention distinct success rate have been reported. Recently treatment with extracellular matrix injection becomes more and more popular to strengthen the joint itself. Since multifactorial in character, the best solution of the treatment modalities should be aimed to resolve possible etiology from different aspects. Team work may be indication to reach satisfied results.

Original languageEnglish
Pages (from-to)223-230
Number of pages8
JournalKaohsiung Journal of Medical Sciences
Issue number4
Publication statusPublished - 2018 Apr


  • Internal derangement
  • Temporomandibular disorder
  • Temporomandibular joint


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