Fungicidal action of hydroxyl radicals generated by ultrasound in water

Atsuo Iwasawa; Keita Saito; Takayuki Mokudai; Masahiro Kohno; Toshihiko Ozawa; Yoshimi Niwano

doi:10.3164/jcbn.08-261

Fungicidal action of hydroxyl radicals generated by ultrasound in water

Atsuo Iwasawa, Keita Saito, Takayuki Mokudai, Masahiro Kohno, Toshihiko Ozawa, Yoshimi Niwano

Research output: Contribution to journal › Article › peer-review

22 Citations (Scopus)

Abstract

It is well known that hydroxyl radicals are generated by ultrasound in water. This study with an electron spin resonance spin-trapping technique showed that hydroxyl radical generation was positively correlated with ultrasound duration and water temperature. The clear fungicidal action against Trichophyton spp. evident by studying cultured cells and the degradation of cytoplasmic and surface structures observed by transmission and scanning electron microscopy suggest that ultrasound in hot water is effective for sterilization of dermatophyte contamination and could be effective for the treatment of tinea infection.

Original language	English
Pages (from-to)	214-218
Number of pages	5
Journal	Journal of Clinical Biochemistry and Nutrition
Volume	45
Issue number	2
DOIs	https://doi.org/10.3164/jcbn.08-261
Publication status	Published - 2009 Sept
Externally published	Yes

Keywords

Electron microscopy
Fungicidal activity
Hydroxyl radical
Trichophyton spp.
Ultrasound

ASJC Scopus subject areas

Medicine (miscellaneous)
Nutrition and Dietetics
Clinical Biochemistry

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10.3164/jcbn.08-261

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title = "Fungicidal action of hydroxyl radicals generated by ultrasound in water",

abstract = "It is well known that hydroxyl radicals are generated by ultrasound in water. This study with an electron spin resonance spin-trapping technique showed that hydroxyl radical generation was positively correlated with ultrasound duration and water temperature. The clear fungicidal action against Trichophyton spp. evident by studying cultured cells and the degradation of cytoplasmic and surface structures observed by transmission and scanning electron microscopy suggest that ultrasound in hot water is effective for sterilization of dermatophyte contamination and could be effective for the treatment of tinea infection.",

keywords = "Electron microscopy, Fungicidal activity, Hydroxyl radical, Trichophyton spp., Ultrasound",

author = "Atsuo Iwasawa and Keita Saito and Takayuki Mokudai and Masahiro Kohno and Toshihiko Ozawa and Yoshimi Niwano",

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AU - Iwasawa, Atsuo

AU - Saito, Keita

AU - Mokudai, Takayuki

AU - Kohno, Masahiro

AU - Ozawa, Toshihiko

AU - Niwano, Yoshimi

PY - 2009/9

Y1 - 2009/9

N2 - It is well known that hydroxyl radicals are generated by ultrasound in water. This study with an electron spin resonance spin-trapping technique showed that hydroxyl radical generation was positively correlated with ultrasound duration and water temperature. The clear fungicidal action against Trichophyton spp. evident by studying cultured cells and the degradation of cytoplasmic and surface structures observed by transmission and scanning electron microscopy suggest that ultrasound in hot water is effective for sterilization of dermatophyte contamination and could be effective for the treatment of tinea infection.

AB - It is well known that hydroxyl radicals are generated by ultrasound in water. This study with an electron spin resonance spin-trapping technique showed that hydroxyl radical generation was positively correlated with ultrasound duration and water temperature. The clear fungicidal action against Trichophyton spp. evident by studying cultured cells and the degradation of cytoplasmic and surface structures observed by transmission and scanning electron microscopy suggest that ultrasound in hot water is effective for sterilization of dermatophyte contamination and could be effective for the treatment of tinea infection.

KW - Electron microscopy

KW - Fungicidal activity

KW - Hydroxyl radical

KW - Trichophyton spp.

KW - Ultrasound

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Fungicidal action of hydroxyl radicals generated by ultrasound in water

Abstract

Keywords

ASJC Scopus subject areas

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