Generalized mucinosis in a patient with erythroderma

Taku Fujimura; Ryuhei Okuyama; Satoshi Nakagawa; Tadashi Terui; Setsuya Aiba

doi:10.1159/000092288

Generalized mucinosis in a patient with erythroderma

Taku Fujimura, Ryuhei Okuyama, Satoshi Nakagawa, Tadashi Terui, Setsuya Aiba

Sense Organs and Rehabilitation Medicine

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Abstract

We describe an 81-year-old Japanese patient with erythroderma overlapping with widespread and symmetrical deposits of mucin in the upper dermis. Clinically, the mucinous lesions on the nape and upper trunk were localized papular mucinosis. Histologically, there was a perivascular infiltrate of lymphohistiocytic cells mingled with plasma cells in the upper dermis but no sclerosis. Immunohistochemical staining revealed that more than 90% of these infiltrating plasma cells produced immunoglobulin λ-chain. Both the erythroderma and generalized mucinosis responded to topical steroid and PUVA therapy. To the best of our knowledge, this is the first case of erythroderma accompanied by generalized mucinosis.

Original language	English
Pages (from-to)	366-369
Number of pages	4
Journal	Dermatology
Volume	212
Issue number	4
DOIs	https://doi.org/10.1159/000092288
Publication status	Published - 2006 May

Keywords

Atypical papular mucinosis
Erythroderma

ASJC Scopus subject areas

Dermatology

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10.1159/000092288

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abstract = "We describe an 81-year-old Japanese patient with erythroderma overlapping with widespread and symmetrical deposits of mucin in the upper dermis. Clinically, the mucinous lesions on the nape and upper trunk were localized papular mucinosis. Histologically, there was a perivascular infiltrate of lymphohistiocytic cells mingled with plasma cells in the upper dermis but no sclerosis. Immunohistochemical staining revealed that more than 90% of these infiltrating plasma cells produced immunoglobulin λ-chain. Both the erythroderma and generalized mucinosis responded to topical steroid and PUVA therapy. To the best of our knowledge, this is the first case of erythroderma accompanied by generalized mucinosis.",

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AU - Fujimura, Taku

AU - Okuyama, Ryuhei

AU - Nakagawa, Satoshi

AU - Terui, Tadashi

AU - Aiba, Setsuya

PY - 2006/5

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N2 - We describe an 81-year-old Japanese patient with erythroderma overlapping with widespread and symmetrical deposits of mucin in the upper dermis. Clinically, the mucinous lesions on the nape and upper trunk were localized papular mucinosis. Histologically, there was a perivascular infiltrate of lymphohistiocytic cells mingled with plasma cells in the upper dermis but no sclerosis. Immunohistochemical staining revealed that more than 90% of these infiltrating plasma cells produced immunoglobulin λ-chain. Both the erythroderma and generalized mucinosis responded to topical steroid and PUVA therapy. To the best of our knowledge, this is the first case of erythroderma accompanied by generalized mucinosis.

AB - We describe an 81-year-old Japanese patient with erythroderma overlapping with widespread and symmetrical deposits of mucin in the upper dermis. Clinically, the mucinous lesions on the nape and upper trunk were localized papular mucinosis. Histologically, there was a perivascular infiltrate of lymphohistiocytic cells mingled with plasma cells in the upper dermis but no sclerosis. Immunohistochemical staining revealed that more than 90% of these infiltrating plasma cells produced immunoglobulin λ-chain. Both the erythroderma and generalized mucinosis responded to topical steroid and PUVA therapy. To the best of our knowledge, this is the first case of erythroderma accompanied by generalized mucinosis.

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Generalized mucinosis in a patient with erythroderma

Abstract

Keywords

ASJC Scopus subject areas

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