Abstract
Recent genetic studies revealed crucial roles of JNK (c-jun N-terminal kinase) activation in cell death. However, the molecular mechanisms underlying JNK-mediated cell death are largely unknown. We present one of the JNK-mediated apoptotic mechanism is regulated by a ubiquitine-proteasome system.
Original language | English |
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Pages (from-to) | 223-226 |
Number of pages | 4 |
Journal | Acta Histochemica et Cytochemica |
Volume | 37 |
Issue number | 4 |
DOIs | |
Publication status | Published - 2004 |
Keywords
- Apoptosis
- ASK1
- IAPs
- JNK
- TRAFs