Glutathione-mediated reversibility of covalent modification of ubiquitin carboxyl-terminal hydrolase L1 by 1,2-naphthoquinone through Cys152, but not Lys4

Pharmacology, Toxicology and Pharmaceutical Science

• 1,2 Naphthoquinone 100%
• Ubiquitin Thiolesterase 100%
• Enzyme 20%
• Glutathione 20%
• Cytotoxicity 10%
• Degenerative Disease 10%
• Enzyme Inhibition 10%
• Neuroblastoma 10%
• Deterioration 10%
• Cell Protein 10%
• Electrophile 10%
• Nerve Degeneration 10%
• Glyceraldehyde 3 Phosphate Dehydrogenase 10%
• Buthionine Sulfoximine 10%

Neuroscience

• Ubiquitin Thiolesterase 100%
• Glutathione 20%
• Enzymes 10%
• Neurodegeneration 10%
• Cell Signaling 10%
• Neuroblastoma 10%
• Cytotoxicity 10%
• Cell Protein 10%
• Enzyme Activity 10%
• Buthionine Sulfoximine 10%
• Neurodegenerative Disorder 10%
• Enzyme Inhibition 10%
• Glyceraldehyde 3 Phosphate Dehydrogenase 10%

Biochemistry, Genetics and Molecular Biology

• Glutathione 20%
• Electrophilicity 20%
• Enzymatic Activity 10%
• Lysozyme 10%
• Signal Transduction 10%
• Enzyme Activity 10%
• Cytotoxicity 10%
• Glyceraldehyde 3-Phosphate Dehydrogenase 10%
• Buthionine Sulfoximine 10%
• Arylation 10%
• Enzyme Inhibition 10%