Haemodynamics and oxygen metabolism in patients after reversible ischaemic attack or minor ischaemic stroke assessed with positron emission tomography

M. Itoh; J. Hatazawa; C. Pozzilli; H. Fukuda; Y. Abe; T. Fujiwara; K. Kubota; K. Yamaguchi; T. Sato; H. Watanabe; T. Ido; T. Matsuzawa

doi:10.1007/BF00341736

Haemodynamics and oxygen metabolism in patients after reversible ischaemic attack or minor ischaemic stroke assessed with positron emission tomography

M. Itoh, J. Hatazawa, C. Pozzilli, H. Fukuda, Y. Abe, T. Fujiwara, K. Kubota, K. Yamaguchi, T. Sato, H. Watanabe, T. Ido, T. Matsuzawa

Cyclotron and Radioisotope Center (CYRIC)

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11 Citations (Scopus)

Abstract

Regional cerebral blood flow (CBF), blood volume (CBV) and oxygen metabolic rate (CMRO2) were evaluated and compared among normals, patients with recent reversible ischaemic attacks (RIAs) and patients with chronic minor infarction using positron emission tomography. Average CBF together with CMRO2 significantly decreased in the infarction group in the middle cerebral artery territory of the affected hemisphere while the mean values for RIAs were intermediate between the other two groups. CBV also reduced, however it was more preserved compared to flow as seen in decreased CBF/CBV values. Significant interhemispheric difference was found in CBF/CBV ratio, but it did not clearly correlate with OEF changes. Higher OEF was noted only in the restricted brain regions of RIAs where CBF showed large hemispheric asymmetry. However, in other regions, the coupled decline of blood flow and metabolism was found which suggests tissue damage or neuronal cell loss in the brain with previous RIA symptoms.

Original language	English
Pages (from-to)	416-421
Number of pages	6
Journal	Neuroradiology
Volume	29
Issue number	5
DOIs	https://doi.org/10.1007/BF00341736
Publication status	Published - 1987 Sept

Keywords

Carotid stenosis
Cerebral blood flow
Cerebral blood volume
Cerebral oxygen metabolism
Positron tomography
Reversible ischaemic attacks

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10.1007/BF00341736

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Itoh, M., Hatazawa, J., Pozzilli, C., Fukuda, H., Abe, Y., Fujiwara, T., Kubota, K., Yamaguchi, K., Sato, T., Watanabe, H., Ido, T., & Matsuzawa, T. (1987). Haemodynamics and oxygen metabolism in patients after reversible ischaemic attack or minor ischaemic stroke assessed with positron emission tomography. Neuroradiology, 29(5), 416-421. https://doi.org/10.1007/BF00341736

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title = "Haemodynamics and oxygen metabolism in patients after reversible ischaemic attack or minor ischaemic stroke assessed with positron emission tomography",

abstract = "Regional cerebral blood flow (CBF), blood volume (CBV) and oxygen metabolic rate (CMRO2) were evaluated and compared among normals, patients with recent reversible ischaemic attacks (RIAs) and patients with chronic minor infarction using positron emission tomography. Average CBF together with CMRO2 significantly decreased in the infarction group in the middle cerebral artery territory of the affected hemisphere while the mean values for RIAs were intermediate between the other two groups. CBV also reduced, however it was more preserved compared to flow as seen in decreased CBF/CBV values. Significant interhemispheric difference was found in CBF/CBV ratio, but it did not clearly correlate with OEF changes. Higher OEF was noted only in the restricted brain regions of RIAs where CBF showed large hemispheric asymmetry. However, in other regions, the coupled decline of blood flow and metabolism was found which suggests tissue damage or neuronal cell loss in the brain with previous RIA symptoms.",

keywords = "Carotid stenosis, Cerebral blood flow, Cerebral blood volume, Cerebral oxygen metabolism, Positron tomography, Reversible ischaemic attacks",

author = "M. Itoh and J. Hatazawa and C. Pozzilli and H. Fukuda and Y. Abe and T. Fujiwara and K. Kubota and K. Yamaguchi and T. Sato and H. Watanabe and T. Ido and T. Matsuzawa",

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doi = "10.1007/BF00341736",

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volume = "29",

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Itoh, M, Hatazawa, J, Pozzilli, C, Fukuda, H, Abe, Y, Fujiwara, T, Kubota, K, Yamaguchi, K, Sato, T, Watanabe, H, Ido, T & Matsuzawa, T 1987, 'Haemodynamics and oxygen metabolism in patients after reversible ischaemic attack or minor ischaemic stroke assessed with positron emission tomography', Neuroradiology, vol. 29, no. 5, pp. 416-421. https://doi.org/10.1007/BF00341736

TY - JOUR

T1 - Haemodynamics and oxygen metabolism in patients after reversible ischaemic attack or minor ischaemic stroke assessed with positron emission tomography

AU - Itoh, M.

AU - Hatazawa, J.

AU - Pozzilli, C.

AU - Fukuda, H.

AU - Abe, Y.

AU - Fujiwara, T.

AU - Kubota, K.

AU - Yamaguchi, K.

AU - Sato, T.

AU - Watanabe, H.

AU - Ido, T.

AU - Matsuzawa, T.

PY - 1987/9

Y1 - 1987/9

N2 - Regional cerebral blood flow (CBF), blood volume (CBV) and oxygen metabolic rate (CMRO2) were evaluated and compared among normals, patients with recent reversible ischaemic attacks (RIAs) and patients with chronic minor infarction using positron emission tomography. Average CBF together with CMRO2 significantly decreased in the infarction group in the middle cerebral artery territory of the affected hemisphere while the mean values for RIAs were intermediate between the other two groups. CBV also reduced, however it was more preserved compared to flow as seen in decreased CBF/CBV values. Significant interhemispheric difference was found in CBF/CBV ratio, but it did not clearly correlate with OEF changes. Higher OEF was noted only in the restricted brain regions of RIAs where CBF showed large hemispheric asymmetry. However, in other regions, the coupled decline of blood flow and metabolism was found which suggests tissue damage or neuronal cell loss in the brain with previous RIA symptoms.

AB - Regional cerebral blood flow (CBF), blood volume (CBV) and oxygen metabolic rate (CMRO2) were evaluated and compared among normals, patients with recent reversible ischaemic attacks (RIAs) and patients with chronic minor infarction using positron emission tomography. Average CBF together with CMRO2 significantly decreased in the infarction group in the middle cerebral artery territory of the affected hemisphere while the mean values for RIAs were intermediate between the other two groups. CBV also reduced, however it was more preserved compared to flow as seen in decreased CBF/CBV values. Significant interhemispheric difference was found in CBF/CBV ratio, but it did not clearly correlate with OEF changes. Higher OEF was noted only in the restricted brain regions of RIAs where CBF showed large hemispheric asymmetry. However, in other regions, the coupled decline of blood flow and metabolism was found which suggests tissue damage or neuronal cell loss in the brain with previous RIA symptoms.

KW - Carotid stenosis

KW - Cerebral blood flow

KW - Cerebral blood volume

KW - Cerebral oxygen metabolism

KW - Positron tomography

KW - Reversible ischaemic attacks

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SN - 0028-3940

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JO - Neuroradiology

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IS - 5

ER -

Haemodynamics and oxygen metabolism in patients after reversible ischaemic attack or minor ischaemic stroke assessed with positron emission tomography

Abstract

Keywords

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