TY - JOUR
T1 - High b-value diffusion-weighted MRI for detecting gallbladder carcinoma
T2 - Preliminary study and results
AU - Sugita, Reiji
AU - Yamazaki, Tetsuro
AU - Furuta, Akemi
AU - Itoh, Kei
AU - Fujita, Naotaka
AU - Takahashi, Shoki
PY - 2009
Y1 - 2009
N2 - The aim of this preliminary study was to retrospectively evaluate the usefulness of high b-value diffusion-weighted MR imaging (DWI) in the detection of gallbladder carcinoma. Fifteen patients with gallbladder carcinoma and 14 other patients were included in this study. All patients and subjects underwent DWI, and images were evaluated by two radiologists. The area under the receiver operating characteristic curve (AUC), apparent diffusion coefficient (ADC) measurement, sensitivity and specificity were calculated. An AUC yielded 0.980 (95% CI, 0.850-0.999) and 0.941 (95% CI, 0.791-0.990) for the two radiologists. The mean sensitivity and specificity were 83.3% and 100%, respectively. The mean ADC value of gallbladder carcinoma was (1.28±0.41)×10-3 mm2/s and that of control gallbladder lesions was (1.92±0.21)×10-3 mm2/s (P<0.01). According to the results of our preliminary study, high b-value DWI might be a useful tool for detecting gallbladder carcinoma by measuring the ADC value and direct visual assessment.
AB - The aim of this preliminary study was to retrospectively evaluate the usefulness of high b-value diffusion-weighted MR imaging (DWI) in the detection of gallbladder carcinoma. Fifteen patients with gallbladder carcinoma and 14 other patients were included in this study. All patients and subjects underwent DWI, and images were evaluated by two radiologists. The area under the receiver operating characteristic curve (AUC), apparent diffusion coefficient (ADC) measurement, sensitivity and specificity were calculated. An AUC yielded 0.980 (95% CI, 0.850-0.999) and 0.941 (95% CI, 0.791-0.990) for the two radiologists. The mean sensitivity and specificity were 83.3% and 100%, respectively. The mean ADC value of gallbladder carcinoma was (1.28±0.41)×10-3 mm2/s and that of control gallbladder lesions was (1.92±0.21)×10-3 mm2/s (P<0.01). According to the results of our preliminary study, high b-value DWI might be a useful tool for detecting gallbladder carcinoma by measuring the ADC value and direct visual assessment.
KW - Diffusion
KW - Gallbladder carcinoma
KW - MRI
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U2 - 10.1007/s00330-009-1322-9
DO - 10.1007/s00330-009-1322-9
M3 - Article
C2 - 19190910
AN - SCOPUS:67349097861
SN - 0938-7994
VL - 19
SP - 1794
EP - 1798
JO - European Radiology
JF - European Radiology
IS - 7
ER -