High-speed chemical imaging inside a microfluidic channel

Ko Ichiro Miyamoto; Akinori Itabashi; Torsten Wagner; Michael J. Schöning; Tatsuo Yoshinobu

doi:10.1016/j.snb.2013.12.090

High-speed chemical imaging inside a microfluidic channel

Ko Ichiro Miyamoto, Akinori Itabashi, Torsten Wagner, Michael J. Schöning, Tatsuo Yoshinobu

Research output: Contribution to journal › Article › peer-review

36 Citations (Scopus)

Abstract

In this study, a high-speed chemical imaging system was developed for visualization of the interior of a microfluidic channel. A microfluidic channel was constructed on the sensor surface of the light-addressable potentiometric sensor (LAPS), on which the ion concentrations could be measured in parallel at up to 64 points illuminated by optical fibers. The temporal change of pH distribution inside the microfluidic channel was recorded at a maximum rate of 100 frames per second (fps). The high frame rate allowed visualization of moving interfaces and plugs in the channel even at a flow velocity of 111 mm/s, which suggests the feasibility of plug-based microfluidic devices for flow-injection analysis (FIA).

Original language	English
Pages (from-to)	521-527
Number of pages	7
Journal	Sensors and Actuators B: Chemical
Volume	194
DOIs	https://doi.org/10.1016/j.snb.2013.12.090
Publication status	Published - 2014 Apr

Keywords

High-speed chemical imaging
Light-addressable potentiometric sensor
Microfluidic channel

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10.1016/j.snb.2013.12.090

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title = "High-speed chemical imaging inside a microfluidic channel",

abstract = "In this study, a high-speed chemical imaging system was developed for visualization of the interior of a microfluidic channel. A microfluidic channel was constructed on the sensor surface of the light-addressable potentiometric sensor (LAPS), on which the ion concentrations could be measured in parallel at up to 64 points illuminated by optical fibers. The temporal change of pH distribution inside the microfluidic channel was recorded at a maximum rate of 100 frames per second (fps). The high frame rate allowed visualization of moving interfaces and plugs in the channel even at a flow velocity of 111 mm/s, which suggests the feasibility of plug-based microfluidic devices for flow-injection analysis (FIA).",

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note = "Funding Information: This work was supported by JSPS Grant-in-Aid for Scientific Research (B) (contract no. 24310098 ). A part of this research was carried out at the Machine Shop Division of Fundamental Technology Center, Research Institute of Electrical Communication, Tohoku University . ",

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doi = "10.1016/j.snb.2013.12.090",

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AU - Itabashi, Akinori

AU - Wagner, Torsten

AU - Schöning, Michael J.

AU - Yoshinobu, Tatsuo

N1 - Funding Information: This work was supported by JSPS Grant-in-Aid for Scientific Research (B) (contract no. 24310098 ). A part of this research was carried out at the Machine Shop Division of Fundamental Technology Center, Research Institute of Electrical Communication, Tohoku University .

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High-speed chemical imaging inside a microfluidic channel

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Keywords

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