High-Speed Volatile Odorant Molecule Dissolving Strategy for Cell-Based Odorant Sensors

Daigo Terutsuki; Hidefumi Mitsuno; Yuki Nishina; Takuya Iio; Takeshi Sakurai; Kohei Sato; Nobuyuki Mase; Ryohei Kanzaki

doi:10.1109/ISOEN.2019.8823288

High-Speed Volatile Odorant Molecule Dissolving Strategy for Cell-Based Odorant Sensors

Daigo Terutsuki, Hidefumi Mitsuno, Yuki Nishina, Takuya Iio, Takeshi Sakurai, Kohei Sato, Nobuyuki Mase, Ryohei Kanzaki

Research output: Chapter in Book/Report/Conference proceeding › Conference contribution

1 Citation (Scopus)

Abstract

Detecting volatile odorant molecules in air is currently a hot topic in biosensors. We propose an ultrafine bubble (UFB)-based dissolution strategy that allows rapid solubilization of odorant molecules with poor water solubility in distilled water (DW). The system dissolved 1-octen-3-ol, a poorly water-soluble molecule responsible for moldy odors, to a concentration of 44.6 μM in DW in one minute with high concentrations of ultrasonic spray-generated UFBs. The responses of Sf21 cells expressing insect odorant receptors to the dissolved 1-octen-3-ol samples were detected through fluorescence microscopy measurements. This method is appropriate for solubilizing airborne odorant molecules that dissolve poorly in water and comprises a practical strategy for cell-based odorant sensor systems.

Original language	English
Title of host publication	ISOEN 2019 - 18th International Symposium on Olfaction and Electronic Nose, Proceedings
Publisher	Institute of Electrical and Electronics Engineers Inc.
ISBN (Electronic)	9781538683279
DOIs	https://doi.org/10.1109/ISOEN.2019.8823288
Publication status	Published - 2019 May
Externally published	Yes
Event	18th International Symposium on Olfaction and Electronic Nose, ISOEN 2019 - Fukuoka, Japan Duration: 2019 May 26 → 2019 May 29

Publication series

Name	ISOEN 2019 - 18th International Symposium on Olfaction and Electronic Nose, Proceedings

Conference

Conference	18th International Symposium on Olfaction and Electronic Nose, ISOEN 2019
Country/Territory	Japan
City	Fukuoka
Period	19/5/26 → 19/5/29

Keywords

Ultrafine bubbles
insect odorant receptor
odorant sensor
ultrasonic spray
volatile odorant molecule

ASJC Scopus subject areas

Signal Processing
Instrumentation

Access to Document

10.1109/ISOEN.2019.8823288

Cite this

Terutsuki, D., Mitsuno, H., Nishina, Y., Iio, T., Sakurai, T., Sato, K., Mase, N., & Kanzaki, R. (2019). High-Speed Volatile Odorant Molecule Dissolving Strategy for Cell-Based Odorant Sensors. In ISOEN 2019 - 18th International Symposium on Olfaction and Electronic Nose, Proceedings [8823288] (ISOEN 2019 - 18th International Symposium on Olfaction and Electronic Nose, Proceedings). Institute of Electrical and Electronics Engineers Inc.. https://doi.org/10.1109/ISOEN.2019.8823288

High-Speed Volatile Odorant Molecule Dissolving Strategy for Cell-Based Odorant Sensors. / Terutsuki, Daigo; Mitsuno, Hidefumi; Nishina, Yuki et al.

ISOEN 2019 - 18th International Symposium on Olfaction and Electronic Nose, Proceedings. Institute of Electrical and Electronics Engineers Inc., 2019. 8823288 (ISOEN 2019 - 18th International Symposium on Olfaction and Electronic Nose, Proceedings).

Research output: Chapter in Book/Report/Conference proceeding › Conference contribution

Terutsuki, D, Mitsuno, H, Nishina, Y, Iio, T, Sakurai, T, Sato, K, Mase, N & Kanzaki, R 2019, High-Speed Volatile Odorant Molecule Dissolving Strategy for Cell-Based Odorant Sensors. in ISOEN 2019 - 18th International Symposium on Olfaction and Electronic Nose, Proceedings., 8823288, ISOEN 2019 - 18th International Symposium on Olfaction and Electronic Nose, Proceedings, Institute of Electrical and Electronics Engineers Inc., 18th International Symposium on Olfaction and Electronic Nose, ISOEN 2019, Fukuoka, Japan, 19/5/26. https://doi.org/10.1109/ISOEN.2019.8823288

Terutsuki D, Mitsuno H, Nishina Y, Iio T, Sakurai T, Sato K et al. High-Speed Volatile Odorant Molecule Dissolving Strategy for Cell-Based Odorant Sensors. In ISOEN 2019 - 18th International Symposium on Olfaction and Electronic Nose, Proceedings. Institute of Electrical and Electronics Engineers Inc. 2019. 8823288. (ISOEN 2019 - 18th International Symposium on Olfaction and Electronic Nose, Proceedings). doi: 10.1109/ISOEN.2019.8823288

Terutsuki, Daigo ; Mitsuno, Hidefumi ; Nishina, Yuki et al. / High-Speed Volatile Odorant Molecule Dissolving Strategy for Cell-Based Odorant Sensors. ISOEN 2019 - 18th International Symposium on Olfaction and Electronic Nose, Proceedings. Institute of Electrical and Electronics Engineers Inc., 2019. (ISOEN 2019 - 18th International Symposium on Olfaction and Electronic Nose, Proceedings).

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abstract = "Detecting volatile odorant molecules in air is currently a hot topic in biosensors. We propose an ultrafine bubble (UFB)-based dissolution strategy that allows rapid solubilization of odorant molecules with poor water solubility in distilled water (DW). The system dissolved 1-octen-3-ol, a poorly water-soluble molecule responsible for moldy odors, to a concentration of 44.6 μM in DW in one minute with high concentrations of ultrasonic spray-generated UFBs. The responses of Sf21 cells expressing insect odorant receptors to the dissolved 1-octen-3-ol samples were detected through fluorescence microscopy measurements. This method is appropriate for solubilizing airborne odorant molecules that dissolve poorly in water and comprises a practical strategy for cell-based odorant sensor systems.",

keywords = "Ultrafine bubbles, insect odorant receptor, odorant sensor, ultrasonic spray, volatile odorant molecule",

author = "Daigo Terutsuki and Hidefumi Mitsuno and Yuki Nishina and Takuya Iio and Takeshi Sakurai and Kohei Sato and Nobuyuki Mase and Ryohei Kanzaki",

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AU - Sakurai, Takeshi

AU - Sato, Kohei

AU - Mase, Nobuyuki

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N2 - Detecting volatile odorant molecules in air is currently a hot topic in biosensors. We propose an ultrafine bubble (UFB)-based dissolution strategy that allows rapid solubilization of odorant molecules with poor water solubility in distilled water (DW). The system dissolved 1-octen-3-ol, a poorly water-soluble molecule responsible for moldy odors, to a concentration of 44.6 μM in DW in one minute with high concentrations of ultrasonic spray-generated UFBs. The responses of Sf21 cells expressing insect odorant receptors to the dissolved 1-octen-3-ol samples were detected through fluorescence microscopy measurements. This method is appropriate for solubilizing airborne odorant molecules that dissolve poorly in water and comprises a practical strategy for cell-based odorant sensor systems.

AB - Detecting volatile odorant molecules in air is currently a hot topic in biosensors. We propose an ultrafine bubble (UFB)-based dissolution strategy that allows rapid solubilization of odorant molecules with poor water solubility in distilled water (DW). The system dissolved 1-octen-3-ol, a poorly water-soluble molecule responsible for moldy odors, to a concentration of 44.6 μM in DW in one minute with high concentrations of ultrasonic spray-generated UFBs. The responses of Sf21 cells expressing insect odorant receptors to the dissolved 1-octen-3-ol samples were detected through fluorescence microscopy measurements. This method is appropriate for solubilizing airborne odorant molecules that dissolve poorly in water and comprises a practical strategy for cell-based odorant sensor systems.

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High-Speed Volatile Odorant Molecule Dissolving Strategy for Cell-Based Odorant Sensors

Abstract

Publication series

Conference

Keywords

ASJC Scopus subject areas

Access to Document

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