Ferromagnetic materials exhibiting low magnetic damping (α) and moderately high-saturation magnetization are required from the viewpoints of generation, transmission, and detection of spin waves. Since spin-to-charge conversion efficiency is another important parameter, high spin mixing conductance (gr↑↓) is the key for efficient spin-to-charge conversion. Full Heusler alloys, e.g., Co2Fe0.4Mn0.6Si (CFMS), which are predicted to be 100% spin-polarized, exhibit low α. However, gr↑↓ at the interface between CFMS and a paramagnet is not fully understood. Here, we report investigations of spin pumping and the inverse spin Hall effect in CFMS/Pt bilayers. Damping analysis indicates the presence of significant spin pumping at the interface of CFMS and Pt, which is also confirmed by the detection of an inverse spin Hall voltage. We show that in CFMS/Pt, gr↑↓ (1.70 × 1020 m−2) and the interface transparency (83%) are higher than the values reported for other ferromagnetic/heavy metal systems. We observed a spin Hall angle of ~0.026 for the CFMS/Pt bilayer system.