Highly enantioselective recognition of dicarboxylic acid substrates by the control of nonlinear responses

Tomohiro Ikeda; Osamu Hirata; Masayuki Takeuchi; Seiji Shinkai

doi:10.1021/ja067001x

Highly enantioselective recognition of dicarboxylic acid substrates by the control of nonlinear responses

Tomohiro Ikeda, Osamu Hirata, Masayuki Takeuchi, Seiji Shinkai

Research output: Contribution to journal › Article › peer-review

60 Citations (Scopus)

Abstract

An allosteric host, in which the molecular information of the chiral guest was precisely introduced, exhibits unconventional enantioselectivity toward the target enantiomer even under the conditions of a -20% enantiomeric excess (ee) mixture within a certain concentration window. This is effected by incorporation of the structural information of the enantiomer into the host and the utilization of multiple equilibrium.

Original language	English
Pages (from-to)	16008-16009
Number of pages	2
Journal	Journal of the American Chemical Society
Volume	128
Issue number	50
DOIs	https://doi.org/10.1021/ja067001x
Publication status	Published - 2006 Dec 20
Externally published	Yes

ASJC Scopus subject areas

Catalysis
Chemistry(all)
Biochemistry
Colloid and Surface Chemistry

Access to Document

10.1021/ja067001x

Cite this

@article{53cf27f03b984a10b43abc6c337ea763,

title = "Highly enantioselective recognition of dicarboxylic acid substrates by the control of nonlinear responses",

abstract = "An allosteric host, in which the molecular information of the chiral guest was precisely introduced, exhibits unconventional enantioselectivity toward the target enantiomer even under the conditions of a -20% enantiomeric excess (ee) mixture within a certain concentration window. This is effected by incorporation of the structural information of the enantiomer into the host and the utilization of multiple equilibrium.",

author = "Tomohiro Ikeda and Osamu Hirata and Masayuki Takeuchi and Seiji Shinkai",

year = "2006",

month = dec,

day = "20",

doi = "10.1021/ja067001x",

language = "English",

volume = "128",

pages = "16008--16009",

journal = "Journal of the American Chemical Society",

issn = "0002-7863",

publisher = "American Chemical Society",

number = "50",

}

TY - JOUR

T1 - Highly enantioselective recognition of dicarboxylic acid substrates by the control of nonlinear responses

AU - Ikeda, Tomohiro

AU - Hirata, Osamu

AU - Takeuchi, Masayuki

AU - Shinkai, Seiji

PY - 2006/12/20

Y1 - 2006/12/20

N2 - An allosteric host, in which the molecular information of the chiral guest was precisely introduced, exhibits unconventional enantioselectivity toward the target enantiomer even under the conditions of a -20% enantiomeric excess (ee) mixture within a certain concentration window. This is effected by incorporation of the structural information of the enantiomer into the host and the utilization of multiple equilibrium.

AB - An allosteric host, in which the molecular information of the chiral guest was precisely introduced, exhibits unconventional enantioselectivity toward the target enantiomer even under the conditions of a -20% enantiomeric excess (ee) mixture within a certain concentration window. This is effected by incorporation of the structural information of the enantiomer into the host and the utilization of multiple equilibrium.

UR - http://www.scopus.com/inward/record.url?scp=33845594872&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=33845594872&partnerID=8YFLogxK

U2 - 10.1021/ja067001x

DO - 10.1021/ja067001x

M3 - Article

C2 - 17165733

AN - SCOPUS:33845594872

SN - 0002-7863

VL - 128

SP - 16008

EP - 16009

JO - Journal of the American Chemical Society

JF - Journal of the American Chemical Society

IS - 50

ER -

Highly enantioselective recognition of dicarboxylic acid substrates by the control of nonlinear responses

Abstract

ASJC Scopus subject areas

Access to Document

Other files and links

Fingerprint

Cite this