Histomorphometric assessments of peri-implant bone around ti-nb-sn alloy implants with low young’s modulus

Naru Shiraishi; Hiroshi Masumoto; Kenta Takahashi; Taichi Tenkumo; Takahisa Anada; Osamu Suzuki; Toru Ogawa; Keiichi Sasaki

doi:10.4012/dmj.2018-376

Histomorphometric assessments of peri-implant bone around ti-nb-sn alloy implants with low young’s modulus

Naru Shiraishi, Hiroshi Masumoto, Kenta Takahashi, Taichi Tenkumo, Takahisa Anada, Osamu Suzuki, Toru Ogawa, Keiichi Sasaki

Research output: Contribution to journal › Article › peer-review

3 Citations (Scopus)

Abstract

Many β-Ti alloys have been developed for, and used in, medical devices because of the corrosion resistance, biocompatibility, and exceptionally low Young’s modulus. The aim of the present study was to investigate the histomorphometric aspects of peri-implant bone around Ti-Nb-Sn alloy implants and compare them with those in the case of commercially pure Ti (Ti). Fluorescent morphological observations of ST-2 cells on the substrate were performed and bone morphogenesis around implants in rat femur was evaluated. There was no difference between the cell morphology on Ti and those on the Ti-Nb-Sn alloy during observation for 24 h. A comparison of the Ti-Nb-Sn alloy implant and the Ti implant showed no significant differences between the bone-to-implant contact ratios or the bone fractions. These results suggest that the biological adaptations with Ti-Nb-Sn implants during a healing period are similar to those with Ti. Ti-Nb-Sn is therefore suitable for use in dental implants.

Original language	English
Pages (from-to)	148-153
Number of pages	6
Journal	Dental Materials Journal
Volume	39
Issue number	1
DOIs	https://doi.org/10.4012/dmj.2018-376
Publication status	Published - 2020

Keywords

Implant
Low Young’s modulus
Ti-Nb-Sn

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10.4012/dmj.2018-376

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title = "Histomorphometric assessments of peri-implant bone around ti-nb-sn alloy implants with low young{\textquoteright}s modulus",

abstract = "Many β-Ti alloys have been developed for, and used in, medical devices because of the corrosion resistance, biocompatibility, and exceptionally low Young{\textquoteright}s modulus. The aim of the present study was to investigate the histomorphometric aspects of peri-implant bone around Ti-Nb-Sn alloy implants and compare them with those in the case of commercially pure Ti (Ti). Fluorescent morphological observations of ST-2 cells on the substrate were performed and bone morphogenesis around implants in rat femur was evaluated. There was no difference between the cell morphology on Ti and those on the Ti-Nb-Sn alloy during observation for 24 h. A comparison of the Ti-Nb-Sn alloy implant and the Ti implant showed no significant differences between the bone-to-implant contact ratios or the bone fractions. These results suggest that the biological adaptations with Ti-Nb-Sn implants during a healing period are similar to those with Ti. Ti-Nb-Sn is therefore suitable for use in dental implants.",

keywords = "Implant, Low Young{\textquoteright}s modulus, Ti-Nb-Sn",

author = "Naru Shiraishi and Hiroshi Masumoto and Kenta Takahashi and Taichi Tenkumo and Takahisa Anada and Osamu Suzuki and Toru Ogawa and Keiichi Sasaki",

note = "Funding Information: This work was supported by a Grant-in-Aid for Scientific Research (No. 25861822) from the Ministry of Education, Culture, Sports, Science and Technology of Japan. The authors are grateful to Shuji HANADA (Institute for Materials Research, Tohoku University) for providing the Ti-Nb-Sn alloy as test samples for this study. This work is a cooperative program (Proposal No. 15G0206 and 16G0207) of the CRDAM-IMR, Tohoku University. Publisher Copyright: {\textcopyright} 2020, Japanese Society for Dental Materials and Devices. All rights reserved.",

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volume = "39",

pages = "148--153",

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AU - Shiraishi, Naru

AU - Masumoto, Hiroshi

AU - Takahashi, Kenta

AU - Tenkumo, Taichi

AU - Anada, Takahisa

AU - Suzuki, Osamu

AU - Ogawa, Toru

AU - Sasaki, Keiichi

N1 - Funding Information: This work was supported by a Grant-in-Aid for Scientific Research (No. 25861822) from the Ministry of Education, Culture, Sports, Science and Technology of Japan. The authors are grateful to Shuji HANADA (Institute for Materials Research, Tohoku University) for providing the Ti-Nb-Sn alloy as test samples for this study. This work is a cooperative program (Proposal No. 15G0206 and 16G0207) of the CRDAM-IMR, Tohoku University. Publisher Copyright: © 2020, Japanese Society for Dental Materials and Devices. All rights reserved.

PY - 2020

Y1 - 2020

N2 - Many β-Ti alloys have been developed for, and used in, medical devices because of the corrosion resistance, biocompatibility, and exceptionally low Young’s modulus. The aim of the present study was to investigate the histomorphometric aspects of peri-implant bone around Ti-Nb-Sn alloy implants and compare them with those in the case of commercially pure Ti (Ti). Fluorescent morphological observations of ST-2 cells on the substrate were performed and bone morphogenesis around implants in rat femur was evaluated. There was no difference between the cell morphology on Ti and those on the Ti-Nb-Sn alloy during observation for 24 h. A comparison of the Ti-Nb-Sn alloy implant and the Ti implant showed no significant differences between the bone-to-implant contact ratios or the bone fractions. These results suggest that the biological adaptations with Ti-Nb-Sn implants during a healing period are similar to those with Ti. Ti-Nb-Sn is therefore suitable for use in dental implants.

AB - Many β-Ti alloys have been developed for, and used in, medical devices because of the corrosion resistance, biocompatibility, and exceptionally low Young’s modulus. The aim of the present study was to investigate the histomorphometric aspects of peri-implant bone around Ti-Nb-Sn alloy implants and compare them with those in the case of commercially pure Ti (Ti). Fluorescent morphological observations of ST-2 cells on the substrate were performed and bone morphogenesis around implants in rat femur was evaluated. There was no difference between the cell morphology on Ti and those on the Ti-Nb-Sn alloy during observation for 24 h. A comparison of the Ti-Nb-Sn alloy implant and the Ti implant showed no significant differences between the bone-to-implant contact ratios or the bone fractions. These results suggest that the biological adaptations with Ti-Nb-Sn implants during a healing period are similar to those with Ti. Ti-Nb-Sn is therefore suitable for use in dental implants.

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Histomorphometric assessments of peri-implant bone around ti-nb-sn alloy implants with low young’s modulus

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Keywords

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