Hollow fiber-optic probe for in vivo Raman measurements

Takashi Katagiri; Yusuke Hattori; Yuichi Komachi; Yuji Matsuura; Hideo Tashiro; Hidetoshi Sato

doi:10.1117/12.686634

Hollow fiber-optic probe for in vivo Raman measurements

Takashi Katagiri, Yusuke Hattori, Yuichi Komachi, Yuji Matsuura, Hideo Tashiro, Hidetoshi Sato

MEN - Biomedical Engineering

Research output: Chapter in Book/Report/Conference proceeding › Conference contribution › peer-review

1 Citation (Scopus)

Abstract

A hollow optical fiber (HOF) Roman probe equipped with a ball lens is developed to study the stomach cancer. The probe generates little Raman scattering or fluorescence noise because the HOF confine light into the air core. In order to maximize the collection efficiency and the spatial resolution, material and size of the ball lens is optimized. The total diameter of the probe head is 640 μm. The probe is useful for measurement of layered sample by the contact mode because it has very short focal length and high depth resolution. In vivo experiments in a stomach of a living rat demonstrate the high viability of the probe for noninvasive diagnosis of the stomach cancer.

Original language	English
Title of host publication	Smart Medical and Biomedical Sensor Technology IV
DOIs	https://doi.org/10.1117/12.686634
Publication status	Published - 2006
Event	Smart Medical and Biomedical Sensor Technology IV - Boston, MA, United States Duration: 2006 Oct 3 → 2006 Oct 4

Publication series

Name	Proceedings of SPIE - The International Society for Optical Engineering
Volume	6380
ISSN (Print)	0277-786X

Conference

Conference	Smart Medical and Biomedical Sensor Technology IV
Country/Territory	United States
City	Boston, MA
Period	06/10/3 → 06/10/4

Keywords

Confocal
Hollow optical fiber
Optical biopsy
Raman spectroscopy

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

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10.1117/12.686634

Cite this

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title = "Hollow fiber-optic probe for in vivo Raman measurements",

abstract = "A hollow optical fiber (HOF) Roman probe equipped with a ball lens is developed to study the stomach cancer. The probe generates little Raman scattering or fluorescence noise because the HOF confine light into the air core. In order to maximize the collection efficiency and the spatial resolution, material and size of the ball lens is optimized. The total diameter of the probe head is 640 μm. The probe is useful for measurement of layered sample by the contact mode because it has very short focal length and high depth resolution. In vivo experiments in a stomach of a living rat demonstrate the high viability of the probe for noninvasive diagnosis of the stomach cancer.",

keywords = "Confocal, Hollow optical fiber, Optical biopsy, Raman spectroscopy",

author = "Takashi Katagiri and Yusuke Hattori and Yuichi Komachi and Yuji Matsuura and Hideo Tashiro and Hidetoshi Sato",

year = "2006",

doi = "10.1117/12.686634",

language = "English",

isbn = "0819464783",

series = "Proceedings of SPIE - The International Society for Optical Engineering",

booktitle = "Smart Medical and Biomedical Sensor Technology IV",

note = "Smart Medical and Biomedical Sensor Technology IV ; Conference date: 03-10-2006 Through 04-10-2006",

}

Katagiri, T, Hattori, Y, Komachi, Y, Matsuura, Y, Tashiro, H & Sato, H 2006, Hollow fiber-optic probe for in vivo Raman measurements. in Smart Medical and Biomedical Sensor Technology IV., 63800X, Proceedings of SPIE - The International Society for Optical Engineering, vol. 6380, Smart Medical and Biomedical Sensor Technology IV, Boston, MA, United States, 06/10/3. https://doi.org/10.1117/12.686634

Hollow fiber-optic probe for in vivo Raman measurements. / Katagiri, Takashi; Hattori, Yusuke; Komachi, Yuichi et al.
Smart Medical and Biomedical Sensor Technology IV. 2006. 63800X (Proceedings of SPIE - The International Society for Optical Engineering; Vol. 6380).

Research output: Chapter in Book/Report/Conference proceeding › Conference contribution › peer-review

TY - GEN

T1 - Hollow fiber-optic probe for in vivo Raman measurements

AU - Katagiri, Takashi

AU - Hattori, Yusuke

AU - Komachi, Yuichi

AU - Matsuura, Yuji

AU - Tashiro, Hideo

AU - Sato, Hidetoshi

PY - 2006

Y1 - 2006

N2 - A hollow optical fiber (HOF) Roman probe equipped with a ball lens is developed to study the stomach cancer. The probe generates little Raman scattering or fluorescence noise because the HOF confine light into the air core. In order to maximize the collection efficiency and the spatial resolution, material and size of the ball lens is optimized. The total diameter of the probe head is 640 μm. The probe is useful for measurement of layered sample by the contact mode because it has very short focal length and high depth resolution. In vivo experiments in a stomach of a living rat demonstrate the high viability of the probe for noninvasive diagnosis of the stomach cancer.

AB - A hollow optical fiber (HOF) Roman probe equipped with a ball lens is developed to study the stomach cancer. The probe generates little Raman scattering or fluorescence noise because the HOF confine light into the air core. In order to maximize the collection efficiency and the spatial resolution, material and size of the ball lens is optimized. The total diameter of the probe head is 640 μm. The probe is useful for measurement of layered sample by the contact mode because it has very short focal length and high depth resolution. In vivo experiments in a stomach of a living rat demonstrate the high viability of the probe for noninvasive diagnosis of the stomach cancer.

KW - Confocal

KW - Hollow optical fiber

KW - Optical biopsy

KW - Raman spectroscopy

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U2 - 10.1117/12.686634

DO - 10.1117/12.686634

M3 - Conference contribution

AN - SCOPUS:33846229612

SN - 0819464783

SN - 9780819464781

T3 - Proceedings of SPIE - The International Society for Optical Engineering

BT - Smart Medical and Biomedical Sensor Technology IV

T2 - Smart Medical and Biomedical Sensor Technology IV

Y2 - 3 October 2006 through 4 October 2006

ER -

Hollow fiber-optic probe for in vivo Raman measurements

Abstract

Publication series

Conference

Keywords

UN SDGs

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