TY - JOUR
T1 - Host-guest chemistry in layer-by-layer assemblies containing Calix[n]arenes and Cucurbit[n]urils
T2 - A review
AU - Akiba, Uichi
AU - Minaki, Daichi
AU - Anzai, Jun Ichi
N1 - Funding Information:
This review has demonstrated that CA[n]s and CB[n]s can be successfully built into LbL This review has demonstrated that CA[n]s and CB[n]s can be successfully built into LbL assemblies assemblies and serve as selective binding sites for ions and molecules. CA[n]-containing LbL films and serve as selective binding sites for ions and molecules. CA[n]-containing LbL films are useful for are useful for the construction of chemical sensors for VOCs and perm-selective membranes for the construction of chemical sensors for VOCs and perm-selective membranes for metal ions. A merit metal ions. A merit of CA[n]s comes from the simple preparation of water-soluble derivatives such of CA[n]s comes from the simple preparation of water-soluble derivatives such as s-CA[n]s, in contrast as s-CA[n]s, in contrast to the limited solubility of unmodified CA[n]s. On the other hand, to the limited solubility of unmodified CA[n]s. On the other hand, CB[n]-containing LbL films and CB[n]-containing LbL films and microcapsules are useful for the construction of molecular microcapsules are useful for the construction of molecular containers and controlled release systems containers and controlled release systems owing to their extremely strong affinity for owing to their extremely strong affinity for positively-charged organic guests such as MV. The selective positively-charged organic guests such as MV. The selective binding properties of CA[n]s and binding properties of CA[n]s and CB[n]s can be further enhanced by combining the host molecules CB[n]s can be further enhanced by combining the host molecules with nanomaterials such as MSNs with nanomaterials such as MSNs and nanopore membranes. Thus, CA[n]sand CB[n]s-modified LbL and nanopore membranes. Thus, CA[n]sand CB[n]s-modified LbL assemblies may be promising assemblies may be promising tools for biomedical applications. tools for biomedical applications. Acknowledgments: This work was supported in part by a Grant-in-Aid (426670010) from the Japan Society for tAhcekPnroowmloetdiognmoefnStsc:ieTnhcies. work was supported in part by a Grant-in-Aid (426670010) from the Japan Society for Author Contributions: Daichi Minaki and Jun-ichi Anzai collected the materials. Uichi Akiba and Jun-ichi Anzai contributed to the preparation of the manuscript. Author Contributions: Daichi Minaki and Jun-ichi Anzai collected the materials. Uichi Akiba and Jun-ichi CAonnzfalii cctosnotrfiIbnutteerde stto: tThhee paruetphaorrastidoenc olafr tehneomcaonnuflsicctrsipotf. interest.
Publisher Copyright:
© 2018 by the authors.
PY - 2018/1/29
Y1 - 2018/1/29
N2 - This review provides an overview of the synthesis of layer-by-layer (LbL) assemblies containing calix[n]arene (CA[n]) and cucurbit[n]uril (CB[n]) and their applications. LbL assemblies, such as thin films and microcapsules, containing selective binding sites have attracted considerable attention because of their potential use in separation and purification, sensors for ions and molecules, and controlled release. CA[n]-containing LbL films have been prepared using sulfonated CA[n] and cationic polymers to construct chemical sensors and molecular containers. CA[n]-containing LbL films deposited on the surface of a porous support are useful as ion-selective membranes that exhibit selective permeability to monovalent ions over multivalent ions. CB[n]s have been used as molecular glues for the construction of LbL films and microcapsules by taking advantage of the strong affinity of CB[n]s to aromatic compounds. CB[n]s form a stable 1:1:1 ternary complex with electron-rich and electron-deficient molecules in LbL films to stabilize the assemblies. CB[n]-containing LbL films can also be deposited on the surfaces of micro templates and nanopore membranes to construct microcapsules for controlled release and nanochannels for selective ion transport, respectively.
AB - This review provides an overview of the synthesis of layer-by-layer (LbL) assemblies containing calix[n]arene (CA[n]) and cucurbit[n]uril (CB[n]) and their applications. LbL assemblies, such as thin films and microcapsules, containing selective binding sites have attracted considerable attention because of their potential use in separation and purification, sensors for ions and molecules, and controlled release. CA[n]-containing LbL films have been prepared using sulfonated CA[n] and cationic polymers to construct chemical sensors and molecular containers. CA[n]-containing LbL films deposited on the surface of a porous support are useful as ion-selective membranes that exhibit selective permeability to monovalent ions over multivalent ions. CB[n]s have been used as molecular glues for the construction of LbL films and microcapsules by taking advantage of the strong affinity of CB[n]s to aromatic compounds. CB[n]s form a stable 1:1:1 ternary complex with electron-rich and electron-deficient molecules in LbL films to stabilize the assemblies. CB[n]-containing LbL films can also be deposited on the surfaces of micro templates and nanopore membranes to construct microcapsules for controlled release and nanochannels for selective ion transport, respectively.
KW - Calix[n]arene
KW - Cucurbit[n]uril
KW - Host-guest complexation
KW - Layer-by-layer assemblies
UR - http://www.scopus.com/inward/record.url?scp=85041477824&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=85041477824&partnerID=8YFLogxK
U2 - 10.3390/polym10020130
DO - 10.3390/polym10020130
M3 - Review article
AN - SCOPUS:85041477824
SN - 2073-4360
VL - 10
JO - Polymers
JF - Polymers
IS - 2
M1 - 130
ER -