TY - JOUR
T1 - Hydration of single-stranded DNA in water studied by infrared spectroscopy
AU - Miyamoto, Ko ichiro
AU - Onodera, Kota
AU - Yamaguchi, Ryo taro
AU - Ishibashi, Ken ichi
AU - Kimura, Yasuo
AU - Niwano, Michio
N1 - Funding Information:
This work was supported by a Grant-of-Aid for Basic Scientific Research (Grant nos. 14205007 and 17206004) from the Ministry of Education, Science, Sports, and Culture of Japan. We also gratefully acknowledge Japan Science and Technology Corporation (JST) for the financial support of the Core Research for Evolution Science and Technology (CREST).
PY - 2007/2/27
Y1 - 2007/2/27
N2 - Hydration of single-stranded DNAs (oligonucleotides) of thymine (dT10) and adenine (dA10) in heavy water has been investigated using infrared absorption spectroscopy in the geometry of multiple internal reflection. Comparison of infrared absorption data with results of ab initio cluster calculation clearly indicates that water molecules are bound to the C{double bond, long}O and N-H bonds of the thymine base, giving rise to a red-shift of the C{double bond, long}O stretching vibration modes, and that the water molecule is site-specifically bound to the thymine base. We find that hydration induces a blue-shift of the ring deformation mode of the adenine base.
AB - Hydration of single-stranded DNAs (oligonucleotides) of thymine (dT10) and adenine (dA10) in heavy water has been investigated using infrared absorption spectroscopy in the geometry of multiple internal reflection. Comparison of infrared absorption data with results of ab initio cluster calculation clearly indicates that water molecules are bound to the C{double bond, long}O and N-H bonds of the thymine base, giving rise to a red-shift of the C{double bond, long}O stretching vibration modes, and that the water molecule is site-specifically bound to the thymine base. We find that hydration induces a blue-shift of the ring deformation mode of the adenine base.
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U2 - 10.1016/j.cplett.2006.12.102
DO - 10.1016/j.cplett.2006.12.102
M3 - Article
AN - SCOPUS:33846796042
SN - 0009-2614
VL - 436
SP - 233
EP - 238
JO - Chemical Physics Letters
JF - Chemical Physics Letters
IS - 1-3
ER -