TY - GEN
T1 - Hydrogel-based imaging sensor for the assay of exercise-dependent metabolic regulation in skeletal muscle cells
AU - Nagamine, Kuniaki
AU - Okamoto, Kohei
AU - Kaji, Hirokazu
AU - Kanzaki, Makoto
AU - Nishizawa, Matsuhiko
PY - 2013
Y1 - 2013
N2 - Two types of hydrogel-based metabolite-responsive imaging sensor sheets were developed for in vitro assay of contraction-dependent metabolic regulation in skeletal muscle cells: one is an oxygen sensor and the other is an Interleukin-6 (IL-6) sensor. These soft, molecularly permeable hydrogel-based sensors were directly laminated to another hydrogel on which myotubes were micropatterned, and displayed usefully measureable changes in local oxygen consumption and IL-6 secretion activity of myotubes upon electrically-induced contraction.
AB - Two types of hydrogel-based metabolite-responsive imaging sensor sheets were developed for in vitro assay of contraction-dependent metabolic regulation in skeletal muscle cells: one is an oxygen sensor and the other is an Interleukin-6 (IL-6) sensor. These soft, molecularly permeable hydrogel-based sensors were directly laminated to another hydrogel on which myotubes were micropatterned, and displayed usefully measureable changes in local oxygen consumption and IL-6 secretion activity of myotubes upon electrically-induced contraction.
KW - Myokine
KW - Oxygen sensor
KW - Skeletal muscle cell
UR - http://www.scopus.com/inward/record.url?scp=84907321512&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=84907321512&partnerID=8YFLogxK
M3 - Conference contribution
AN - SCOPUS:84907321512
SN - 9781632666246
T3 - 17th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2013
SP - 1505
EP - 1507
BT - 17th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2013
PB - Chemical and Biological Microsystems Society
T2 - 17th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2013
Y2 - 27 October 2013 through 31 October 2013
ER -