TY - GEN
T1 - Hydrogel-based sealed microchambers for simple and cost-effective cell culture and drug testing
AU - Yoshida, Shotaro
AU - Sumomozawa, Kensuke
AU - Nishizawa, Matsuhiko
N1 - Funding Information:
This work was partly supported by MIRAI and Center of Innovation Program (COI-Stream) from Japan Science and Technology Agency (JST) and Grant-in-Aid for Scientific Research A (25246016) from the Ministry of Education, Culture, Sports, Science and Technology, Japan.
Publisher Copyright:
© 2019 CBMS-0001.
PY - 2019
Y1 - 2019
N2 - We propose a hydrogel-based sealed microchamber that enables easy and simple cell culture and drug testing. Cells can be cultured inside the sealed microchambers for the permeability of the hydrogel microchambers to nutrients. Also, drug testing from outside the sealed microchamber is demonstrated. The molecularly permeable, sealed microchambers enables simple and cost-effective medium exchange during cell culture and drug testing with cells stably positioned, which is useful in culturing floating cell spheroids for regenerative medicine and drug testing.
AB - We propose a hydrogel-based sealed microchamber that enables easy and simple cell culture and drug testing. Cells can be cultured inside the sealed microchambers for the permeability of the hydrogel microchambers to nutrients. Also, drug testing from outside the sealed microchamber is demonstrated. The molecularly permeable, sealed microchambers enables simple and cost-effective medium exchange during cell culture and drug testing with cells stably positioned, which is useful in culturing floating cell spheroids for regenerative medicine and drug testing.
KW - Cardiomyocytes
KW - HiPSC
KW - Hydrogel
KW - Molecular permeability
KW - Organic electronics
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M3 - Conference contribution
AN - SCOPUS:85094938215
T3 - 23rd International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2019
SP - 1504
EP - 1505
BT - 23rd International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2019
PB - Chemical and Biological Microsystems Society
T2 - 23rd International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2019
Y2 - 27 October 2019 through 31 October 2019
ER -