Hydrolyses of calcium phosphates-allografts composite in physiological solutions

Takuya Nomoto, Keiji Haraguchi, Shunro Yamaguchi, Nobuhiko Sugano, Hirokazu Nakayama, Tohru Sekino, Koichi Niihara

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10 Citations (Scopus)


Hydrolysis of calcium phosphates cement-allografts composite in calf serum and that in saline were examined in comparison with those of the calcium phosphates cement in both the solutions. The calcium phosphates cement consists of α-tricalcium phosphate (α-TCP), tetracalcium phosphate (TetCP), dicalcium phosphate dihydrate (DCPD), and hydroxyapatite (HAP), which is clinically used as Biopex. In the hydrolyses of Biopex-allografts composite in both the solutions, the calcium phosphates cement was transformed into HAP. On the other hand, in the hydrolyses of Biopex, HAP was formed after 1 day and octacalcium phosphate (OCP) was gradually formed after 7 days. In the presence of allografts, plate-like crystals were deposited and in the absence of allografts, needle-like crystals were deposited in both the solutions. By the addition of allografts, the hydrolysis process of the calcium phosphates cement was significantly changed.

Original languageEnglish
Pages (from-to)379-385
Number of pages7
JournalJournal of Materials Science: Materials in Medicine
Issue number4
Publication statusPublished - 2006 Apr

ASJC Scopus subject areas

  • Biophysics
  • Bioengineering
  • Biomaterials
  • Biomedical Engineering


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