TY - JOUR
T1 - Identification of two cDNAs for human actin-related proteins (Arps) that have remarkable similarity to conventional actin
AU - Harata, Masahiko
AU - Nishimori, Katsuhiko
AU - Hatta, Shunsuke
PY - 2001/12/3
Y1 - 2001/12/3
N2 - We identified two cDNAs coding for the novel human actin-related proteins (Arps) hArpM1 and hArpM2. Both of them show remarkable similarity to conventional actin, and the ATP-binding motif and nuclear-export signals of actin are highly conserved. Their mRNAs are expressed in all tested human tissues, but in smaller amounts than that of actin. These features suggest that hArpM1 and M2 are involved in cytoskeletal organization like other cytoplasmic Arp subfamilies.
AB - We identified two cDNAs coding for the novel human actin-related proteins (Arps) hArpM1 and hArpM2. Both of them show remarkable similarity to conventional actin, and the ATP-binding motif and nuclear-export signals of actin are highly conserved. Their mRNAs are expressed in all tested human tissues, but in smaller amounts than that of actin. These features suggest that hArpM1 and M2 are involved in cytoskeletal organization like other cytoplasmic Arp subfamilies.
KW - ATP binding
KW - Actin-related protein
KW - Nuclear export signal
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U2 - 10.1016/S0167-4781(01)00315-3
DO - 10.1016/S0167-4781(01)00315-3
M3 - Article
C2 - 11750065
AN - SCOPUS:0035803912
SN - 0167-4781
VL - 1522
SP - 130
EP - 133
JO - Biochimica et Biophysica Acta - Gene Structure and Expression
JF - Biochimica et Biophysica Acta - Gene Structure and Expression
IS - 2
ER -