@article{f4270f8116df44cfab5f762c6cffe8cb,
title = "Identification of two teleost homologs of the Drosophila sex determination factor, transformer-2 in medaka (Oryzias latipes)",
abstract = "Transformer-2 (Tra2), an RNA-binding protein, is an important regulator in Drosophila sex determination. In vertebrates, however, the role of Tra2 homologues is not known. We identified two teleost homologues of Tra2, which we named Tra2a and Tra2b, in medaka (Oryzias latipes). Furthermore, we demonstrated that both Tra2 mRNAs were predominantly expressed in germ cells of both sexes before the onset of sex differentiation, suggesting that both Tra2 homologues might be involved in the sex differentiation in medaka.",
keywords = "Germ cell, Medaka, Sex differentiation, Teleost, Tra2, Transformer-2",
author = "Eri Shiraishi and Hideo Imazato and Takashi Yamamoto and Hayato Yokoi and Abe, {Shin Ichi} and Takeshi Kitano",
note = "Funding Information: We are grateful to Drs Marie A. DiBerardino and Mitsuyo Kishida for editing and critically reading the manuscript. We also thank Professor Yoshitaka Nagahama for his helpful advice. FLF II stock was kindly provided by Drs Wakamatsu and Ozato of the Nagoya University. This work was supported in part by CREST (Core Research for Evolutional Science and Technology) of JST (Japan Science Technology Corporation).",
year = "2004",
month = jul,
doi = "10.1016/j.mod.2004.04.013",
language = "English",
volume = "121",
pages = "991--996",
journal = "Mechanisms of Development",
issn = "0925-4773",
publisher = "Elsevier BV",
number = "7-8",
}