Abstract
German patients suspected of having Creutzfeldt-Jakob disease (CJD) and related diseases were studied pathologically. The immunohistochemical findings after hydrolytic autoclaving pretreatment sensitively detected the synaptic-type deposition of the protease-resistant isoform of the prion protein (PrP(res)) which thus served to establish the consensus diagnosis of CJD.
Original language | English |
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Pages (from-to) | 358-360 |
Number of pages | 3 |
Journal | Clinical Neuropathology |
Volume | 15 |
Issue number | 6 |
Publication status | Published - 1996 Nov |
Keywords
- Creutzfeldt-Jakob disease
- Hydrolytic autoclaving pretreatment
- Immunohistochemistry
- Prions
ASJC Scopus subject areas
- Pathology and Forensic Medicine
- Neurology
- Clinical Neurology