German patients suspected of having Creutzfeldt-Jakob disease (CJD) and related diseases were studied pathologically. The immunohistochemical findings after hydrolytic autoclaving pretreatment sensitively detected the synaptic-type deposition of the protease-resistant isoform of the prion protein (PrP(res)) which thus served to establish the consensus diagnosis of CJD.
|Number of pages||3|
|Publication status||Published - 1996 Nov|
- Creutzfeldt-Jakob disease
- Hydrolytic autoclaving pretreatment
ASJC Scopus subject areas
- Pathology and Forensic Medicine
- Clinical Neurology