Impact of end-stage renal disease in patients with critical limb ischaemia undergoing infrapopliteal intervention

Osami Kawarada; Yoshiaki Yokoi; Akihiro Higashimori; Masahiko Fujihara; Shingo Sakamoto; Masaharu Ishihara; Satoshi Yasuda; Hisao Ogawa

doi:10.4244/EIJV10I6A129

Impact of end-stage renal disease in patients with critical limb ischaemia undergoing infrapopliteal intervention

Osami Kawarada, Yoshiaki Yokoi, Akihiro Higashimori, Masahiko Fujihara, Shingo Sakamoto, Masaharu Ishihara, Satoshi Yasuda, Hisao Ogawa

Research output: Contribution to journal › Article › peer-review

19 Citations (Scopus)

Abstract

Aims: This study aimed to investigate the impact of end-stage renal disease (ESRD) on clinical outcomes following infrapopliteal intervention in critical limb ischaemia patients with tissue loss.

Methods and results: This retrospective single-centre study enrolled 92 consecutive patients (117 limbs) undergoing infrapopliteal intervention for the treatment of ischaemic tissue loss. The primary outcomes were the wound healing rate, the clinically driven reintervention rate and the limb salvage rate. The secondary outcome was amputation-free survival. The pedal arch was significantly (p=0.002) more diseased in ESRD patients than in non-ESRD patients. ESRD patients demonstrated a significantly lower wound healing rate (hazard ratio [HR], 0.552; 95- CI: 0.319-0.957; p=0.034) and

Conclusions: ESRD patients yielded a more affected pedal arch and were at approximately twice the risk of wound healing failure, need for reintervention, and death or major amputation compared to non-ESRD patients.

Original language	English
Journal	EuroIntervention
Volume	10
Issue number	6
DOIs	https://doi.org/10.4244/EIJV10I6A129
Publication status	Published - 2014 Oct 1
Externally published	Yes

Keywords

Angioplasty
Critical limb disease
Peripheral obstructive disease

ASJC Scopus subject areas

Cardiology and Cardiovascular Medicine

Access to Document

10.4244/EIJV10I6A129

Cite this

@article{8b7368229a674ee8967809929239772f,

title = "Impact of end-stage renal disease in patients with critical limb ischaemia undergoing infrapopliteal intervention",

abstract = "Aims: This study aimed to investigate the impact of end-stage renal disease (ESRD) on clinical outcomes following infrapopliteal intervention in critical limb ischaemia patients with tissue loss.Methods and results: This retrospective single-centre study enrolled 92 consecutive patients (117 limbs) undergoing infrapopliteal intervention for the treatment of ischaemic tissue loss. The primary outcomes were the wound healing rate, the clinically driven reintervention rate and the limb salvage rate. The secondary outcome was amputation-free survival. The pedal arch was significantly (p=0.002) more diseased in ESRD patients than in non-ESRD patients. ESRD patients demonstrated a significantly lower wound healing rate (hazard ratio [HR], 0.552; 95- CI: 0.319-0.957; p=0.034) andConclusions: ESRD patients yielded a more affected pedal arch and were at approximately twice the risk of wound healing failure, need for reintervention, and death or major amputation compared to non-ESRD patients.",

keywords = "Angioplasty, Critical limb disease, Peripheral obstructive disease",

author = "Osami Kawarada and Yoshiaki Yokoi and Akihiro Higashimori and Masahiko Fujihara and Shingo Sakamoto and Masaharu Ishihara and Satoshi Yasuda and Hisao Ogawa",

year = "2014",

month = oct,

day = "1",

doi = "10.4244/EIJV10I6A129",

language = "English",

volume = "10",

journal = "EuroIntervention",

issn = "1774-024X",

publisher = "EuroPCR",

number = "6",

}

TY - JOUR

T1 - Impact of end-stage renal disease in patients with critical limb ischaemia undergoing infrapopliteal intervention

AU - Kawarada, Osami

AU - Yokoi, Yoshiaki

AU - Higashimori, Akihiro

AU - Fujihara, Masahiko

AU - Sakamoto, Shingo

AU - Ishihara, Masaharu

AU - Yasuda, Satoshi

AU - Ogawa, Hisao

PY - 2014/10/1

Y1 - 2014/10/1

N2 - Aims: This study aimed to investigate the impact of end-stage renal disease (ESRD) on clinical outcomes following infrapopliteal intervention in critical limb ischaemia patients with tissue loss.Methods and results: This retrospective single-centre study enrolled 92 consecutive patients (117 limbs) undergoing infrapopliteal intervention for the treatment of ischaemic tissue loss. The primary outcomes were the wound healing rate, the clinically driven reintervention rate and the limb salvage rate. The secondary outcome was amputation-free survival. The pedal arch was significantly (p=0.002) more diseased in ESRD patients than in non-ESRD patients. ESRD patients demonstrated a significantly lower wound healing rate (hazard ratio [HR], 0.552; 95- CI: 0.319-0.957; p=0.034) andConclusions: ESRD patients yielded a more affected pedal arch and were at approximately twice the risk of wound healing failure, need for reintervention, and death or major amputation compared to non-ESRD patients.

AB - Aims: This study aimed to investigate the impact of end-stage renal disease (ESRD) on clinical outcomes following infrapopliteal intervention in critical limb ischaemia patients with tissue loss.Methods and results: This retrospective single-centre study enrolled 92 consecutive patients (117 limbs) undergoing infrapopliteal intervention for the treatment of ischaemic tissue loss. The primary outcomes were the wound healing rate, the clinically driven reintervention rate and the limb salvage rate. The secondary outcome was amputation-free survival. The pedal arch was significantly (p=0.002) more diseased in ESRD patients than in non-ESRD patients. ESRD patients demonstrated a significantly lower wound healing rate (hazard ratio [HR], 0.552; 95- CI: 0.319-0.957; p=0.034) andConclusions: ESRD patients yielded a more affected pedal arch and were at approximately twice the risk of wound healing failure, need for reintervention, and death or major amputation compared to non-ESRD patients.

KW - Angioplasty

KW - Critical limb disease

KW - Peripheral obstructive disease

UR - http://www.scopus.com/inward/record.url?scp=84908266433&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=84908266433&partnerID=8YFLogxK

U2 - 10.4244/EIJV10I6A129

DO - 10.4244/EIJV10I6A129

M3 - Article

C2 - 25330507

AN - SCOPUS:84908266433

SN - 1774-024X

VL - 10

JO - EuroIntervention

JF - EuroIntervention

IS - 6

ER -

Impact of end-stage renal disease in patients with critical limb ischaemia undergoing infrapopliteal intervention

Abstract

Keywords

ASJC Scopus subject areas

Access to Document

Other files and links

Fingerprint

Cite this