TY - JOUR
T1 - Improving the Electrochemical Imaging Sensitivity of Scanning Electrochemical Microscopy-Scanning Ion Conductance Microscopy by Using Electrochemical Pt Deposition
AU - Şen, Mustafa
AU - Takahashi, Yasufumi
AU - Matsumae, Yoshiharu
AU - Horiguchi, Yoshiko
AU - Kumatani, Akichika
AU - Ino, Kosuke
AU - Shiku, Hitoshi
AU - Matsue, Tomokazu
N1 - Publisher Copyright:
© 2015 American Chemical Society.
PY - 2015/3/17
Y1 - 2015/3/17
N2 - We fabricated a platinum-based double barrel probe for scanning electrochemical microscopy-scanning ion conductance microscopy (SECM-SICM) by electrodepositing platinum onto the carbon nanoelectrode of the double barrel probe. The deposition conditions were optimized to attain highly sensitive electrochemical measurements and imaging. Simultaneous SECM-SICM imaging of electrochemical features and noncontact topography by using the optimized probe afforded high-resolution images of epidermal growth factor receptors (EGFR) on the membrane surface of the A431 cells. (Figure Presented).
AB - We fabricated a platinum-based double barrel probe for scanning electrochemical microscopy-scanning ion conductance microscopy (SECM-SICM) by electrodepositing platinum onto the carbon nanoelectrode of the double barrel probe. The deposition conditions were optimized to attain highly sensitive electrochemical measurements and imaging. Simultaneous SECM-SICM imaging of electrochemical features and noncontact topography by using the optimized probe afforded high-resolution images of epidermal growth factor receptors (EGFR) on the membrane surface of the A431 cells. (Figure Presented).
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U2 - 10.1021/acs.analchem.5b00027
DO - 10.1021/acs.analchem.5b00027
M3 - Article
AN - SCOPUS:84925004176
SN - 0003-2700
VL - 87
SP - 3484
EP - 3489
JO - Analytical Chemistry
JF - Analytical Chemistry
IS - 6
ER -