TY - GEN
T1 - In search for a better stent
T2 - 39th Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBC 2017
AU - Putra, Narendra Kurnia
AU - Palar, Pramudita Satria
AU - Anzai, Hitomi
AU - Shimoyama, Koji
AU - Ohta, Makoto
N1 - Funding Information:
*Research supported by Doctorate Scholarship Grant from Indonesia Endowment Fund for Education, Ministry of Finance, Republic of Indonesia, JSPS Core-to-Core and ImPACT Program. N.K.Putra is with Graduate School of Engineering, Tohoku University, Aoba, Sendai 980-8577, Japan (corresponding author to provide phone: +81 22 207 5224; fax: e-mail: naren@biofluid.ifs.tohoku.ac.jp). P.S.Palar is with Institute of Fluid Science, Tohoku University, Katahira, Sendai 980-8577, Japan (e-mail: palar@edge.ifs.tohoku.ac.jp). H.Anzai is with Frontier Institute for Interdisciplinary Science, Tohoku University, Sendai 980-8578, Japan (e-mail: anzai@biofluid.ifs.ac.jp). K.Shimoyama is with Institute of Fluid Science, Tohoku University, Sendai 980-8577, Japan (e-mail: shimoyama@edge.ifs.tohoku.ac.jp) M.Ohta is with the Institute of Fluid Science, Tohoku University, Sendai 980-8577, Japan (email: ohta@biofluid.ifs.tohoku.ac.jp)
Funding Information:
N.K.P thanks for the support from Indonesia Endowment of Education Fund (LPDP). N.K.P and M.O. thanks JSPS Core-to-Core A. Advanced Research Networks, “International research core on smart layered materials and structures for energy saving” and ImPACT Program.
Publisher Copyright:
© 2017 IEEE.
PY - 2017/9/13
Y1 - 2017/9/13
N2 - Stenting is known as one of the main treatment procedure for some intravascular abnormalities such as stenosis and aneurysm. In recent years, stent optimization has been conducted by several research groups in order to increase its treatment efficacy. If we can observe post-deployment behavior on the blood vessel with respect to different stent designs, this observation will be useful in the design process. Kriging surrogate model based on fluid flow simulation on a deformed vessel wall was developed in order to observe this behavior. Multi-objectives optimization was performed with configurations of gap and size as design variables. In this research, percentage of low wall shear stress (WSS) area and average mechanical stress along the deployment area were set as the objective functions. We can recommend that strut with medium size around 100 - 250 micron with a relatively big inter-strut gap is suitable for achieving the optimize criteria. This is because on this range, acceptable optimized value of both objectives functions are successfully obtained.
AB - Stenting is known as one of the main treatment procedure for some intravascular abnormalities such as stenosis and aneurysm. In recent years, stent optimization has been conducted by several research groups in order to increase its treatment efficacy. If we can observe post-deployment behavior on the blood vessel with respect to different stent designs, this observation will be useful in the design process. Kriging surrogate model based on fluid flow simulation on a deformed vessel wall was developed in order to observe this behavior. Multi-objectives optimization was performed with configurations of gap and size as design variables. In this research, percentage of low wall shear stress (WSS) area and average mechanical stress along the deployment area were set as the objective functions. We can recommend that strut with medium size around 100 - 250 micron with a relatively big inter-strut gap is suitable for achieving the optimize criteria. This is because on this range, acceptable optimized value of both objectives functions are successfully obtained.
KW - Computational simulations
KW - Kriging
KW - Multi-objective optimization
KW - Stent
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U2 - 10.1109/EMBC.2017.8037081
DO - 10.1109/EMBC.2017.8037081
M3 - Conference contribution
C2 - 29060125
AN - SCOPUS:85032204605
T3 - Proceedings of the Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBS
SP - 1344
EP - 1347
BT - 2017 39th Annual International Conference of the IEEE Engineering in Medicine and Biology Society
PB - Institute of Electrical and Electronics Engineers Inc.
Y2 - 11 July 2017 through 15 July 2017
ER -