In silico design control of the trade-off balance in robustness and fragility of logical circuits using DNA nanostructures

Miki Hirabayashi; Ibuki Kawamata; Masami Hagiya; Hiroaki Kojima; Kazuhiro Oiwa

doi:10.1109/NANO.2012.6321946

In silico design control of the trade-off balance in robustness and fragility of logical circuits using DNA nanostructures

Miki Hirabayashi, Ibuki Kawamata, Masami Hagiya, Hiroaki Kojima, Kazuhiro Oiwa

ENG - Robotics

Research output: Chapter in Book/Report/Conference proceeding › Conference contribution › peer-review

1 Citation (Scopus)

Abstract

The logical computation using a self-assembly process of DNA nanostructures can provide unbreakable cryptosystems or intelligent molecular robots. Focusing on the trade-off problem between the error-free robustness for stability and the error-tolerable fragility for error correction through reconnections, we present in silico analyses and propose adjustments of indirect factors to control the balance between the two. Computer simulations are helpful to characterize target problems and search optimized solutions to improve developing systems. It is expected that our results will contribute to the construction of important platform technologies for reliable DNA applications.

Original language	English
Title of host publication	2012 12th IEEE International Conference on Nanotechnology, NANO 2012
DOIs	https://doi.org/10.1109/NANO.2012.6321946
Publication status	Published - 2012
Event	2012 12th IEEE International Conference on Nanotechnology, NANO 2012 - Birmingham, United Kingdom Duration: 2012 Aug 20 → 2012 Aug 23

Publication series

Name	Proceedings of the IEEE Conference on Nanotechnology
ISSN (Print)	1944-9399
ISSN (Electronic)	1944-9380

Conference

Conference	2012 12th IEEE International Conference on Nanotechnology, NANO 2012
Country/Territory	United Kingdom
City	Birmingham
Period	12/8/20 → 12/8/23

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10.1109/NANO.2012.6321946

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Hirabayashi, M., Kawamata, I., Hagiya, M., Kojima, H., & Oiwa, K. (2012). In silico design control of the trade-off balance in robustness and fragility of logical circuits using DNA nanostructures. In 2012 12th IEEE International Conference on Nanotechnology, NANO 2012 Article 6321946 (Proceedings of the IEEE Conference on Nanotechnology). https://doi.org/10.1109/NANO.2012.6321946

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title = "In silico design control of the trade-off balance in robustness and fragility of logical circuits using DNA nanostructures",

abstract = "The logical computation using a self-assembly process of DNA nanostructures can provide unbreakable cryptosystems or intelligent molecular robots. Focusing on the trade-off problem between the error-free robustness for stability and the error-tolerable fragility for error correction through reconnections, we present in silico analyses and propose adjustments of indirect factors to control the balance between the two. Computer simulations are helpful to characterize target problems and search optimized solutions to improve developing systems. It is expected that our results will contribute to the construction of important platform technologies for reliable DNA applications.",

author = "Miki Hirabayashi and Ibuki Kawamata and Masami Hagiya and Hiroaki Kojima and Kazuhiro Oiwa",

year = "2012",

doi = "10.1109/NANO.2012.6321946",

language = "English",

isbn = "9781467321983",

series = "Proceedings of the IEEE Conference on Nanotechnology",

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Hirabayashi, M, Kawamata, I, Hagiya, M, Kojima, H & Oiwa, K 2012, In silico design control of the trade-off balance in robustness and fragility of logical circuits using DNA nanostructures. in 2012 12th IEEE International Conference on Nanotechnology, NANO 2012., 6321946, Proceedings of the IEEE Conference on Nanotechnology, 2012 12th IEEE International Conference on Nanotechnology, NANO 2012, Birmingham, United Kingdom, 12/8/20. https://doi.org/10.1109/NANO.2012.6321946

In silico design control of the trade-off balance in robustness and fragility of logical circuits using DNA nanostructures. / Hirabayashi, Miki; Kawamata, Ibuki; Hagiya, Masami et al.
2012 12th IEEE International Conference on Nanotechnology, NANO 2012. 2012. 6321946 (Proceedings of the IEEE Conference on Nanotechnology).

Research output: Chapter in Book/Report/Conference proceeding › Conference contribution › peer-review

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T1 - In silico design control of the trade-off balance in robustness and fragility of logical circuits using DNA nanostructures

AU - Hirabayashi, Miki

AU - Kawamata, Ibuki

AU - Hagiya, Masami

AU - Kojima, Hiroaki

AU - Oiwa, Kazuhiro

PY - 2012

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N2 - The logical computation using a self-assembly process of DNA nanostructures can provide unbreakable cryptosystems or intelligent molecular robots. Focusing on the trade-off problem between the error-free robustness for stability and the error-tolerable fragility for error correction through reconnections, we present in silico analyses and propose adjustments of indirect factors to control the balance between the two. Computer simulations are helpful to characterize target problems and search optimized solutions to improve developing systems. It is expected that our results will contribute to the construction of important platform technologies for reliable DNA applications.

AB - The logical computation using a self-assembly process of DNA nanostructures can provide unbreakable cryptosystems or intelligent molecular robots. Focusing on the trade-off problem between the error-free robustness for stability and the error-tolerable fragility for error correction through reconnections, we present in silico analyses and propose adjustments of indirect factors to control the balance between the two. Computer simulations are helpful to characterize target problems and search optimized solutions to improve developing systems. It is expected that our results will contribute to the construction of important platform technologies for reliable DNA applications.

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T3 - Proceedings of the IEEE Conference on Nanotechnology

BT - 2012 12th IEEE International Conference on Nanotechnology, NANO 2012

T2 - 2012 12th IEEE International Conference on Nanotechnology, NANO 2012

Y2 - 20 August 2012 through 23 August 2012

ER -

In silico design control of the trade-off balance in robustness and fragility of logical circuits using DNA nanostructures

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