Independent validation of the japanese version of the EORTC QLQ-C15-PAL for patients with advanced cancer

Mitsunori Miyashita, Makoto Wada, Tatsuya Morita, Mayumi Ishida, Hideki Onishi, Yasutsuna Sasaki, Masaru Narabayashi, Tomomi Wada, Mei Matsubara, Chizuko Takigawa, Takuya Shinjo, Akihiko Suga, Satoshi Inoue, Masayuki Ikenaga, Hiroyuki Kohara, Satoru Tsuneto, Yasuo Shima

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11 Citations (Scopus)


Context Although the psychometric properties of the Japanese version of the European Organization for Research and Treatment of Cancer Quality of Life Questionnaire-Core 15-Palliative Care (EORTC QLQ-C15-PAL) have been examined previously, that study had several limitations, for example, small sample size. Objectives To examine the validity and reliability, including test-retest reliability, of the Japanese version of EORTC QLQ-C15-PAL for cancer patients with metastasis or recurrence. Methods A cross-sectional anonymous questionnaire was administered to cancer patients who were being treated on an oncology inpatient ward, in an oncology outpatient clinic, and in seven inpatient palliative units in Japan, from August 2007 to March 2008. Results Data from a total of 312 cancer patients were analyzed. The proportion of missing values was less than 4% for all items. The factor structure was reproduced identically with the original EORTC QLQ-C15-PAL, English version. The correlation of subscales showed a reasonable matrix. Cronbach's alpha coefficients were 0.76 to 0.86, and intraclass correlation coefficients, which indicate test-retest reliability, ranged from 0.52 to 0.77. All subscales, especially physical functioning, fatigue, and pain, were significantly correlated with self-reported Eastern Cooperative Oncology Group performance status. Conclusion The Japanese version of EORTC QLQ-C15-PAL has sufficient validity, acceptable reliability, and feasibility for patients with advanced cancer.

Original languageEnglish
Pages (from-to)953-959
Number of pages7
JournalJournal of Pain and Symptom Management
Issue number5
Publication statusPublished - 2015 May 1


  • Palliative care
  • advanced cancer patients
  • neoplasms
  • quality of life
  • questionnaires


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