Induction therapy of tissue regeneration based on tissue engineering induction therapy of tissue regeneration for chronic fibrotic diseases

Masaya Yamamoto, Yersuhiko Tabata, Masaya Yamamoto

Research output: Contribution to journalArticlepeer-review

Abstract

Regenerative medical therapy based on the self-repairing potential of patients has been clinically tried to allow to induce tissue regeneration at a lost or seriously impaired tissue for disease treatment. Recently basic biology and medicine have been developed to manifest the molecular mechanisms of tissue regeneration repairing for chronic fibrosis. Thus, based on the natural potential to induce tissue regeneration, a therapeutic trial for fibrotic diseases with drug delivery system is highly expected. After digested and degraded a fibrotic tissue is repaired based on the potential of the surrounding healthy tissue to induce tissue regeneration. This paper describes this new concept of regenerative therapy of internal medicine by introducing some concrete examples.

Original languageEnglish
Pages (from-to)110-117
Number of pages8
JournalDrug Delivery System
Volume20
Issue number2
DOIs
Publication statusPublished - 2005

Keywords

  • chronic fibrosis disease
  • growth factor
  • molecular target therapy
  • regenerative induction therapy

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