Regenerative medical therapy based on the self-repairing potential of patients has been clinically tried to allow to induce tissue regeneration at a lost or seriously impaired tissue for disease treatment. Recently basic biology and medicine have been developed to manifest the molecular mechanisms of tissue regeneration repairing for chronic fibrosis. Thus, based on the natural potential to induce tissue regeneration, a therapeutic trial for fibrotic diseases with drug delivery system is highly expected. After digested and degraded a fibrotic tissue is repaired based on the potential of the surrounding healthy tissue to induce tissue regeneration. This paper describes this new concept of regenerative therapy of internal medicine by introducing some concrete examples.
- chronic fibrosis disease
- growth factor
- molecular target therapy
- regenerative induction therapy