Epitaxial La2NiMnO6 films were grown on (100)-oriented SrTiO3 and (LaAlO3) 0.3-(SrAl0.5Ta0.5O3)0.7 (LSAT) substrates under various growth conditions by pulsed laser deposition. Ferromagnetism and transport properties of B-site-ordered perovskite are greatly influenced by growth conditions. Optimum growth conditions of epitaxial La 2NiMnO6 films, which exhibit the ferromagnetism similar to bulk properties, are different for SrTiO3 and LSAT substrates probably due to the difference in surface migration. Since the initial stage of epitaxial growth might vary with the type of substrates, the ordering of Ni and Mn ions is different. Therefore, the ferromagnetism of La2NiMnO 6 depends on the epitaxial growth conditions and type of substrates.