Influence of three remineralization materials on physicochemical structure of demineralized enamel

Jinmei Lei, Jinxin Guo, Dongjie Fu, Yake Wang, Xijin Du, Liqun Zhou, Cui Huang

Research output: Contribution to journalArticlepeer-review

2 Citations (Scopus)


This study aimed to evaluate the effect of three inorganic materials:casein phosphopeptide-amorphous calcium phosphate (CPP-ACP), calcium sodium phosphosilicate (CSP) and sodium fluoride (NaF) on their remineralization potential. CPP-ACP, CSP and NaF were applicated in demineralized enamel for 4 h and then all enamel samples were immersed in remineralization solution. After 10 days, all samples were prepared for microhardness test, scanning electron microscopy (SEM) observation and the elemental level (%) analysis by energy dispersive X-ray spectroscopy (EDX). The surface microhardness (SMH) values of three experimental groups were significantly higher than that of control group (P<0.05). The SMH value of NaF group was significantly higher than other experimental groups (P<0.05). The SEM micrographs showed that three remineralization materials caused distinct morphological changes and remineralized deposits were different from each other. EDX elemental analysis showed that there were significant differences in the Ca (wt%) and Ca:P molar ratio of the enamel layer among control and experimental groups. The Ca (wt%) and Ca:P molar ratio in NaF group were significantly higher than those of other experimental groups. There were no significant differences in P (wt%) among control and experimental groups (P<0.05). Three remineralization materials used in our study had the potential of remineralizing the demineralized enamel. NaF is the best and most feasible choice to be used in remineralizing the demineralized enamel.

Original languageEnglish
Pages (from-to)410-416
Number of pages7
JournalJournal Wuhan University of Technology, Materials Science Edition
Issue number2
Publication statusPublished - 2014 Apr
Externally publishedYes


  • elemental analysis
  • microhardness
  • remineralization materials
  • surface morphology

ASJC Scopus subject areas

  • Materials Science(all)


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