Innovative technology for tissue disruption by explosive-induced shock waves

Tetsuya Kodama, Hiroshi Uenohara, Kazuyoshi Takayama

Research output: Contribution to journalArticlepeer-review

28 Citations (Scopus)


We have developed a novel, less invasive, shock wave source that can be introduced into an arbitrary position in a human body percutaneously. Using this technique we can disrupt cells locally. The shock wave source consists of an explosive, an optical fiber, a balloon catheter, and a Nd:YAG laser, which generates a spherical explosive shock wave. The destructive potential of the present source for injuring tissue was confirmed and the subsequent cell elongation and split in the direction of the shock wave has been observed.

Original languageEnglish
Pages (from-to)1459-1466
Number of pages8
JournalUltrasound in Medicine and Biology
Issue number9
Publication statusPublished - 1998 Dec


  • Balloon catheter
  • Cell damage
  • Explosive
  • Shear force
  • Shock wave
  • Tissue damage


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