Insulin signaling: GLUT4 vesicles exit via the exocyst

Makoto Kanzaki, Jeffrey E. Pessin

Research output: Contribution to journalReview articlepeer-review

54 Citations (Scopus)


The localization of the GTP-binding protein TC10 to lipid raft microdomains has been suggested to play a role in the stimulation of GLUT4 translocation. The exocyst has now been identified as a downstream target for TC10, directing GLUT4-containing vesicles to the site of fusion.

Original languageEnglish
Pages (from-to)R574-R576
JournalCurrent Biology
Issue number14
Publication statusPublished - 2003 Jul 15


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