Intercomparison of Dose Distribution between Gamma Knife and C-arm-mounted Linac

Keiichi Nakagawa, Masao Tago, Kouji Shibata, Naoki Nakamura, Hideomi Yamashita, Kenshiro Shiraishi, Atsuro Terahara, Daiki Kato, Shinsuke Kato, Yoshio Hosoi, Masahiro Shin, Kuni Ohtomo

Research output: Contribution to journalArticlepeer-review

1 Citation (Scopus)


Although the Gamma Knife is widely used as a standard tool of radiosurgery for intracranial diseases, recent innovations in medical accelerators have actualized equivalent dose distribution. Most commonly, multiple non-coplanar arc beams through a combination of gantry and couch rotations are used in linac-based radiosurgery, but beam entry geometry is different from that with the Gamma Knife. We have developed a C-arm-mounted medical accelerator and realized conical beam entry without couch rotation. A combination of several conical rotation beams with different C-arm angles comprises multi-orbit dynamic conical radiation therapy (MODCRT) and resembles radiation beam entry with the Gamma Knife. Intercomparison of dose distributions and dose-volume histograms for the same brain tumor demonstrated that MODCRT delivers a similar dose fall-off pattern to that obtained with the Gamma Knife, though the low-dose spread patterns differ.

Original languageEnglish
Pages (from-to)178-182
Number of pages5
JournalRadiation Medicine - Medical Imaging and Radiation Oncology
Issue number4
Publication statusPublished - 2003 Jul


  • C-arm linac
  • Dose distribution
  • Gamma Knife
  • Radiosurgery


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